Interactor 1: DHI1 (P28845)
11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) (EC 1.1.1.146) (7-oxosteroid reductase) (EC 1.1.1.201) (Corticosteroid 11-beta-dehydrogenase isozyme 1) (Short chain dehydrogenase/reductase family 26C member 1)
Gene: HSD11B1

Interactor 2: DHI1 (P28845)
11-beta-hydroxysteroid dehydrogenase 1 (11-DH) (11-beta-HSD1) (EC 1.1.1.146) (7-oxosteroid reductase) (EC 1.1.1.201) (Corticosteroid 11-beta-dehydrogenase isozyme 1) (Short chain dehydrogenase/reductase family 26C member 1)
Gene: HSD11B1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 21325058
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains adh_short~adh_short
Common GO terms GO:0005496 - steroid binding
GO:0005789 - endoplasmic reticulum membrane
GO:0006706 - steroid catabolic process
GO:0016020 - membrane
GO:0030324 - lung development
and 6 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 292
Hs

1 292
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Ss
+ At
+ At
+ Ec
+ At
+ At
+ At
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024