HitPredict

Interactor 1: CXB2 (P29033)
Gap junction beta-2 protein (Connexin-26) (Cx26)
Gene: GJB2

Interactor 2: CXB2 (P29033)
Gap junction beta-2 protein (Connexin-26) (Cx26)
Gene: GJB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.793

The method score is based on:

Property Details
Experiments 17551008, 19340074
Identification Methods 3D electron microscopy, transmission electron microscopy, x-ray crystallography, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Connexin~Connexin
Common GO terms GO:0002931 - response to ischemia
GO:0005243 - gap junction channel activity
GO:0005509 - calcium ion binding
GO:0005793 - endoplasmic reticulum-Golgi intermediate compartment
GO:0005886 - plasma membrane
and 23 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 226
Hs

1 226
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Last updated: 15 Jul 2024