HitPredict

Interactor 1: PHOP (P23836)
Transcriptional regulatory protein PhoP
Gene: PHOP

Interactor 2: PHOQ (P23837)
Sensor protein PhoQ (EC 2.7.13.3) (EC 3.1.3.-) (Sensor histidine protein kinase/phosphatase PhoQ)
Gene: PHOQ

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.696

Property	Details
Experiments	16176121, 15522865
Identification Methods	phosphotransferase assay, affinity chromatography technology
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 223 Ec			1 486
+	Ec
		499520 CUSR_ECOLI (1-222): 5.68e-72: 220: 32.74		CUSS_ECOLI (119-477): 3.53e-70: 233: 18.93
+	Mx
		1167421 Q1DCL7_MYXXD (3-221): 8.79e-76: 230: 28.13		Q1D333_MYXXD (176-484): 9.7e-64: 215: 17.38
+	Ec
		469950 PHOB_ECOLI (2-223): 1.94e-80: 241: 32.89		PHOR_ECOLI (211-486): 6.29e-58: 199: 21.33
+	Mx
		1167386 Q1D1K9_MYXXD (2-223): 2.73e-72: 220: 30.05		Q1D333_MYXXD (176-484): 9.7e-64: 215: 17.38
+	Mx
		1167417 Q1D8M8_MYXXD (3-222): 2.37e-71: 218: 31.98		Q1D333_MYXXD (176-484): 9.7e-64: 215: 17.38
+	Mx
		1167190 Q1D1K9_MYXXD (2-223): 2.73e-72: 220: 30.05		Q1CVV2_MYXXD (237-483): 1.21e-59: 211: 20.46
+	Ss
		1001179 P72948_SYNY3 (2-221): 2.2e-74: 226: 30.87		Q55475_SYNY3 (193-478): 3.33e-59: 201: 20.46
+	Ss
		1200905 Q55942_SYNY3 (1-221): 7.14e-75: 227: 32.14		Q55941_SYNY3 (118-482): 3.48e-58: 200: 18.44
+	Mx
		1167399 Q1D8M8_MYXXD (3-222): 2.37e-71: 218: 31.98		Q1D1W0_MYXXD (176-481): 1.5e-60: 208: 23.15
+	Ec
		497559 OMPR_ECOLI (2-220): 1.24e-70: 217: 33.04		ENVZ_ECOLI (191-477): 2.43e-60: 206: 19.31
+	Ec
		722830 BAER_ECOLI (2-222): 1.85e-69: 214: 31.70		BAES_ECOLI (69-480): 7.08e-61: 208: 16.52
+	Mx
		1167394 Q1D4T4_MYXXD (3-222): 1.22e-68: 211: 32.90		Q1D1W0_MYXXD (176-481): 1.5e-60: 208: 23.15
+	Mx
		1167395 Q1D6S6_MYXXD (1-223): 4.29e-68: 210: 33.93		Q1D1W0_MYXXD (176-481): 1.5e-60: 208: 23.15
+	Ec
		469877 CREB_ECOLI (3-221): 4.58e-69: 212: 33.78		CREC_ECOLI (127-476): 5.42e-60: 206: 20.45
+	Mx
		1167380 Q1D6S6_MYXXD (1-223): 4.29e-68: 210: 33.93		Q1D1K8_MYXXD (201-486): 1.81e-59: 204: 23.83
+	Cv
		1409027 Q9ABD5_CAUVC (3-222): 4.52e-76: 230: 34.53		Q9ABD9_CAUVC (259-481): 8.63e-43: 159: 18.56
+	Ss
		1200900 RPPA_SYNY3 (1-222): 7.58e-72: 220: 35.78		RPPB_SYNY3 (271-477): 1.4e-44: 164: 25.11
+	Mx
		1167442 Q1D4T4_MYXXD (3-222): 1.22e-68: 211: 32.90		Q1D8M1_MYXXD (270-478): 4.52e-45: 171: 21.36
+	Mx
		1167476 Q1D8M8_MYXXD (3-222): 2.37e-71: 218: 31.98		Q1D6S5_MYXXD (213-477): 1.49e-43: 161: 21.32
+	Ec
		1003817 HPRR_ECOLI (1-222): 1.71e-71: 218: 28.38		HPRS_ECOLI (171-480): 1.52e-42: 158: 20.87