Interactor 1: T2EA (P29083)
General transcription factor IIE subunit 1 (General transcription factor IIE 56 kDa subunit) (Transcription initiation factor IIE subunit alpha) (TFIIE-alpha)
Gene: GTF2E1

Interactor 2: CDK7 (P50613)
Cyclin-dependent kinase 7 (EC 2.7.11.22) (EC 2.7.11.23) (39 kDa protein kinase) (p39 Mo15) (CDK-activating kinase 1) (Cell division protein kinase 7) (Serine/threonine-protein kinase 1) (TFIIH basal transcription factor complex kinase subunit)
Gene: CDK7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 25492609, 29568061, 15282296, 23064645
Identification Methods pull down, proximity labelling technology, enzymatic study
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006366 - transcription by RNA polymerase II
GO:0006367 - transcription initiation at RNA polymerase II promoter
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 439
Hs

1 346
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024