HitPredict

Interactor 1: EPHA8 (P29322)
Ephrin type-A receptor 8 (EC 2.7.10.1) (EPH- and ELK-related kinase) (EPH-like kinase 3) (EK3) (hEK3) (Tyrosine-protein kinase receptor EEK)
Gene: EPHA8

Interactor 2: CAC1C (Q13936)
Voltage-dependent L-type calcium channel subunit alpha-1C (Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle) (Voltage-gated calcium channel subunit alpha Cav1.2)
Gene: CACNA1C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37207277
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030425 - dendrite
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1005 Hs			1 2221
+	Hs
		872439 EPHA5_HUMAN (2-1001): 0: 1242: 57.21		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047091 EPHA7_HUMAN (5-1005): 0: 1236: 56.16		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872644 EPHA4_HUMAN (8-1005): 0: 1220: 55.92		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872613 EPHB1_HUMAN (31-999): 0: 1215: 51.53		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665598 EPHB2_HUMAN (31-1005): 0: 1211: 49.95		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		665395 EPHA3_HUMAN (24-1001): 0: 1208: 55.66		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		1047303 EPHA6_HUMAN (1-1005): 0: 1199: 52.23		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		412186 FYN_HUMAN (629-900): 6.44e-59: 213: 41.76		CAC1C_HUMAN (1-2221): 0: 1887: 100.00
+	Hs
		872476 EPHA5_HUMAN (2-1001): 0: 1242: 57.21		SCN2A_HUMAN (1221-1548): 8.66e-16: 86.5: 16.45
+	Hs
		242616 FYN_HUMAN (629-900): 6.44e-59: 213: 41.76		CAC1F_HUMAN (1860-2191): 6.18e-21: 103: 24.14