HitPredict

Interactor 1: PABP1 (P29341)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: Pabpc1

Interactor 2: AIRE (Q9Z0E3)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog) (APECED protein homolog)
Gene: AIRE

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20085707
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 636 Mm			1 552
+	Hs
		217429 PABP1_HUMAN (1-636): 0: 596: 99.69		AIRE_HUMAN (17-549): 2.65e-119: 364: 70.28
+	Hs
		516483 PABP1_HUMAN (1-636): 0: 596: 99.69		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		1018458 PABP4_HUMAN (1-635): 0: 550: 74.54		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Hs
		516522 PABP1_HUMAN (1-636): 0: 596: 99.69		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		516595 PABP1_HUMAN (1-636): 0: 596: 99.69		KMT2C_HUMAN (285-552): 1.18e-23: 108: 14.59
+	Hs
		516745 PABP1_HUMAN (1-636): 0: 596: 99.69		TRI33_HUMAN (345-516): 8.78e-15: 79.8: 18.50
+	Hs
		1031332 PABP4_HUMAN (1-635): 0: 550: 74.54		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		516645 PABP1_HUMAN (1-636): 0: 596: 99.69		NSD1_HUMAN (216-466): 1.91e-09: 62.9: 17.72
+	Hs
		582257 NUCL_HUMAN (3-92): 4.18e-20: 96.8: 32.22		CHD3_HUMAN (32-431): 3.08e-43: 168: 15.17
+	Sc
		376840 PABP_YEAST (184-377): 5.46e-33: 135: 25.51		JHD2_YEAST (285-353): 5.93e-21: 99.1: 37.50
+	Hs
		582297 NUCL_HUMAN (3-92): 4.18e-20: 96.8: 32.22		CHD4_HUMAN (66-540): 6.09e-24: 109: 12.50
+	Hs
		331720 NUCL_HUMAN (3-92): 4.18e-20: 96.8: 32.22		NSD2_HUMAN (216-391): 2.02e-12: 72.1: 21.35