HitPredict

Interactor 1: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 864 Hs			1 152
+	Hs
		666567 LTK_HUMAN (1-864): 0: 763: 100.00		UB2D3_HUMAN (4-149): 1.46e-78: 230: 45.89
+	Hs
		896566 ALK_HUMAN (4-851): 0: 701: 54.51		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		609235 FGFR3_HUMAN (100-834): 2.96e-137: 429: 20.99		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		609211 FGFR3_HUMAN (100-834): 2.96e-137: 429: 20.99		UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46
+	Hs
		435592 IGF1R_HUMAN (298-854): 3.35e-128: 419: 27.39		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		896558 EPHA6_HUMAN (388-809): 1.88e-109: 362: 24.74		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		445838 ROS1_HUMAN (510-813): 5.35e-80: 285: 45.93		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		896454 NTRK3_HUMAN (502-778): 1.77e-54: 205: 36.76		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00
+	Hs
		896418 ROR1_HUMAN (504-778): 1.86e-53: 202: 40.00		UBE2N_HUMAN (1-152): 1.51e-73: 218: 100.00