HitPredict

Interactor 1: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 35384245
Identification Methods affinity chromatography technology, proximity labelling technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0043066 - negative regulation of apoptotic process
GO:0043235 - receptor complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 864
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024