HitPredict

Interactor 1: LTK (P29376)
Leukocyte tyrosine kinase receptor (EC 2.7.10.1) (Protein tyrosine kinase 1)
Gene: LTK

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 864 Hs			1 1294
+	Hs
		1357257 ALK_HUMAN (4-851): 0: 701: 54.51		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		609608 FGFR3_HUMAN (100-834): 2.96e-137: 429: 20.99		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		872505 EPHA5_HUMAN (389-809): 8.73e-124: 400: 26.02		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1083908 NTRK2_HUMAN (475-778): 2.43e-61: 224: 38.07		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		385710 NTRK1_HUMAN (502-786): 7.75e-60: 220: 41.64		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		1081646 NTRK3_HUMAN (502-778): 1.77e-54: 205: 36.76		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Hs
		725069 ALK_HUMAN (4-851): 0: 701: 54.51		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		725268 ALK_HUMAN (4-851): 0: 701: 54.51		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		665375 EPHA3_HUMAN (388-798): 3.64e-124: 400: 27.30		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		384384 NTRK1_HUMAN (502-786): 7.75e-60: 220: 41.64		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		384385 NTRK1_HUMAN (502-786): 7.75e-60: 220: 41.64		MYH10_HUMAN (762-1135): 7.28e-10: 65.8: 15.54
+	Hs
		385783 NTRK1_HUMAN (502-786): 7.75e-60: 220: 41.64		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72