Protein: GPX3
Glutathione peroxidase-like peroxiredoxin HYR1 (EC 1.11.1.24) (Glutathione peroxidase homolog 3) (GPx 3) (Hydrogen peroxide resistance protein 1) (Oxidant receptor peroxidase 1) (Phospholipid hydroperoxide glutathione peroxidase 3) (PHGPx3)

Gene: GPX3, HYR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 37
UniProt ID: P40581

Gene Ontology (top 5):
GO:0004602 - glutathione peroxidase activity
GO:0005739 - mitochondrion
GO:0005758 - mitochondrial intermembrane space
GO:0005782 - peroxisomal matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

626513

AP1
AP-1-like transcription factor YAP1

3

1

Small-scale

0.651

High

827061

GPX3
Glutathione peroxidase-like peroxiredoxin HYR1

1

2

Small-scale

0.647

High

359022

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

2

2

Small-scale

0.624

High

579556

HSC82
ATP-dependent molecular chaperone HSC82

2

4

High-throughput

0.584

High

733664

GLNA
Glutamine synthetase

2

1

Small-scale

0.579

High

797934

YBP1
YAP1-binding protein 1

2

0

Small-scale

0.569

High

827066

DAK1
Dihydroxyacetone kinase 1

2

0

Small-scale

0.569

High

817326

MSRA
Peptide methionine sulfoxide reductase

2

0

Small-scale

0.559

High

791967

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.518

High

827065

ALO
D-arabinono-1,4-lactone oxidase

1

0

High-throughput

0.518

High

827068

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

1

1

High-throughput

0.508

High

780114

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

Small-scale

0.505

High

796271

RFS1
Protein RFS1

1

1

High-throughput

0.494

High

827067

PDR12
ATP-dependent permease PDR12

1

1

High-throughput

0.494

High

827069

TPO3
Polyamine transporter 3

1

1

High-throughput

0.494

High

827073

YB029
UPF0768 protein YBL029C-A

1

1

High-throughput

0.494

High

392871

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.479

High

739392

ZUO1
Zuotin

1

1

Small-scale

0.479

High

607461

GLRX2
Glutaredoxin-2

1

0

Small-scale

0.458

High

781053

T2EA
Transcription initiation factor IIE subunit alpha

1

0

Small-scale

0.458

High

827070

THI3
Thiamine metabolism regulatory protein THI3

1

0

Small-scale

0.458

High

602508

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.457

High

805671

YHS2
MIP18 family protein YHR122W

1

1

High-throughput

0.457

High

827071

FMP45
SUR7 family protein FMP45

1

1

High-throughput

0.457

High

818976

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

610163

PDI
Protein disulfide-isomerase

1

5

Small-scale

0.437

High

666662

AP2
AP-1-like transcription factor YAP2

1

1

Small-scale

0.437

High

707339

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

528598

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.282

High

827072

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.282

High

745560

NGR1
Negative growth regulatory protein NGR1

1

0

High-throughput

0.269

Low

827064

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

0

High-throughput

0.265

Low

585500

KCY
Uridylate kinase

1

0

High-throughput

0.249

Low

827062

PTR3
SPS-sensor component PTR3

1

0

Small-scale

0.249

Low

503714

YB39B
Uncharacterized protein YBL039W-B

1

0

High-throughput

0.238

Low

827063

THG1
tRNA(His) guanylyltransferase

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025