Interactor 1: CASP1 (P29452)
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Gene: CASP1

Interactor 2: PANX1 (Q9JIP4)
Pannexin-1 [Cleaved into: Caspase-activated pannexin-1 (Caspase-activated PANX1)]
Gene: PANX1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 25327779
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0032730 - positive regulation of interleukin-1 alpha production
GO:0032731 - positive regulation of interleukin-1 beta production
GO:0032991 - protein-containing complex
GO:0033198 - response to ATP
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 402
Mm

1 426
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024