Interactor 1: CASP1 (P29466)
Caspase-1 (CASP-1) (EC 3.4.22.36) (Interleukin-1 beta convertase) (IL-1BC) (Interleukin-1 beta-converting enzyme) (ICE) (IL-1 beta-converting enzyme) (p45) [Cleaved into: Caspase-1 subunit p20; Caspase-1 subunit p10]
Gene: CASP1
Interactor 2: CAR18 (P57730)
Caspase recruitment domain-containing protein 18 (Caspase-1 inhibitor Iceberg)
Gene: CARD18
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.49 | 1.00 | 0.701 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27043298 |
| Identification Methods | molecular sieving, transmission electron microscopy, pull down |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD |
| Common GO terms | GO:0032991 - protein-containing complex GO:0042981 - regulation of apoptotic process GO:0050700 - CARD domain binding GO:0050727 - regulation of inflammatory response GO:0072557 - IPAF inflammasome complex and 3 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
