Interactor 1: MCM2 (P29469)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2)
Gene: MCM2

Interactor 2: ORC5 (P50874)
Origin recognition complex subunit 5 (Origin recognition complex 53 kDa subunit)
Gene: ORC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.901

The method score is based on:

Property Details
Experiments 23851460, 34882090, 23603117, 24234446
Identification Methods anti bait coimmunoprecipitation, fluorescent resonance energy transfer, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MCM_lid~ORC5_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
and 2 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 868
Sc

1 479
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024