Interactor 1: NOS3 (P29474)
Nitric oxide synthase 3 (EC 1.14.13.39) (Constitutive NOS) (cNOS) (EC-NOS) (NOS type III) (NOSIII) (Nitric oxide synthase, endothelial) (Endothelial NOS) (eNOS)
Gene: NOS3

Interactor 2: ACTN2 (P35609)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 1.00 0.762

The method score is based on:

Property Details
Experiments 21163940, 18180332
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Flavodoxin_1
Common GO terms GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0043267 - negative regulation of potassium ion transport
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 1203
Hs

1 894
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024