Protein: KEL1
Kelch repeat-containing protein 1

Gene: KEL1
Organism: Saccharomyces cerevisiae S288C
Interactions: 98
UniProt ID: P38853

Gene Ontology (top 5):
GO:0000755 - cytogamy
GO:0001100 - negative regulation of exit from mitosis
GO:0005628 - prospore membrane
GO:0005737 - cytoplasm
GO:0005934 - cellular bud tip

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

806044

KEL2
Kelch repeat-containing protein 2

10

18

Small-scale

0.755

High

460969

LTE1
Guanine nucleotide exchange factor LTE1

6

2

Small-scale

0.732

High

806021

KEL1
Kelch repeat-containing protein 1

5

18

Small-scale

0.710

High

806024

YM11
Uncharacterized protein YMR124W

4

1

Small-scale

0.688

High

743206

PP12
Serine/threonine-protein phosphatase PP1-2

4

4

High-throughput

0.687

High

560695

KIN2
Serine/threonine-protein kinase KIN2

3

6

High-throughput

0.669

High

560603

KIN1
Serine/threonine protein kinase KIN1

3

6

High-throughput

0.653

High

748840

SWE1
Mitosis inhibitor protein kinase SWE1

2

12

High-throughput

0.628

High

694201

BUD14
Bud site selection protein 14

3

0

Small-scale

0.627

High

523897

HSP71
Heat shock protein SSA1

3

8

High-throughput

0.624

High

726143

2AAA
Protein phosphatase PP2A regulatory subunit A

2

5

High-throughput

0.621

High

654717

SPA2
Protein SPA2

2

9

High-throughput

0.613

High

779750

DYHC
Dynein heavy chain, cytoplasmic

2

2

High-throughput

0.595

High

806023

END3
Actin cytoskeleton-regulatory complex protein END3

2

1

High-throughput

0.595

High

806026

LIS1
Nuclear distribution protein PAC1

2

10

High-throughput

0.595

High

364518

CDK1
Cyclin-dependent kinase 1

1

4

High-throughput

0.561

High

599358

FUS3
Mitogen-activated protein kinase FUS3

1

5

Small-scale

0.561

High

544820

SSB1
Ribosome-associated molecular chaperone SSB1

2

10

High-throughput

0.552

High

806025

MBO1
Gamma tubulin complex adapter SPC72

2

1

High-throughput

0.543

High

662085

MPIP
M-phase inducer phosphatase

1

1

High-throughput

0.536

High

751173

BCK2
Protein BCK2

1

1

High-throughput

0.536

High

806027

BEM2
GTPase-activating protein BEM2/IPL2

1

9

High-throughput

0.536

High

704894

KIP2
Kinesin-like protein KIP2

1

2

High-throughput

0.515

High

437918

KAPC
cAMP-dependent protein kinase type 3

1

4

High-throughput

0.501

High

806040

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

3

High-throughput

0.501

High

470013

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.493

High

623852

MYO2
Myosin-2

1

9

High-throughput

0.481

High

646035

KIN3
Serine/threonine-protein kinase KIN3

1

15

High-throughput

0.481

High

735620

SMY1
Kinesin-related protein SMY1

1

6

High-throughput

0.481

High

796303

FL2D
Protein MUM2

1

1

High-throughput

0.481

High

803290

ETP1
RING finger protein ETP1

1

3

High-throughput

0.481

High

806031

PEA2
Protein PEA2

1

1

Small-scale

0.481

High

806047

NST1
Stress response protein NST1

1

18

High-throughput

0.481

High

806060

GYP5
GTPase-activating protein GYP5

1

5

High-throughput

0.481

High

579354

HSC82
ATP-dependent molecular chaperone HSC82

1

16

High-throughput

0.479

High

618344

CDC42
Cell division control protein 42

1

3

Small-scale

0.479

High

667086

CG22
G2/mitotic-specific cyclin-2

1

2

Small-scale

0.479

High

747841

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

776568

DEF1
RNA polymerase II degradation factor 1

1

2

Small-scale

0.479

High

806034

FKS2
1,3-beta-glucan synthase component GSC2

1

3

High-throughput

0.479

High

806049

CDC14
Tyrosine-protein phosphatase CDC14

1

2

Small-scale

0.479

High

806050

KIN4
Serine/threonine-protein kinase KIN4

1

3

Small-scale

0.479

High

736970

CDC3
Cell division control protein 3

1

0

High-throughput

0.460

High

746431

SSO1
Protein SSO1

1

0

High-throughput

0.460

High

750654

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

806035

SPR3
Sporulation-regulated protein 3

1

0

High-throughput

0.460

High

806038

BUD27
Bud site selection protein 27

1

0

High-throughput

0.460

High

806048

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

806058

ARR1
Arsenical-resistance protein ARR1

1

0

High-throughput

0.460

High

94556

STE2
Pheromone alpha factor receptor

1

0

Small-scale

0.458

High

636927

FAR1
Cyclin-dependent kinase inhibitor FAR1

1

0

Small-scale

0.458

High

677270

MET14
Karyogamy protein KAR4

1

0

Small-scale

0.458

High

796228

FIG1
Factor-induced gene 1 protein

1

0

Small-scale

0.458

High

806057

FUS2
Nuclear fusion protein FUS2

1

0

Small-scale

0.458

High

386701

TBB
Tubulin beta chain

1

1

High-throughput

0.445

High

392709

HSP82
ATP-dependent molecular chaperone HSP82

1

16

High-throughput

0.445

High

453591

PYR1
Multifunctional protein URA2

1

6

High-throughput

0.445

High

486167

TBA1
Tubulin alpha-1 chain

1

2

High-throughput

0.445

High

526656

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

592238

VATB
V-type proton ATPase subunit B

1

3

High-throughput

0.445

High

675989

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

737403

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

3

High-throughput

0.445

High

806029

HSP7E
Heat shock protein SSC3, mitochondrial

1

9

High-throughput

0.445

High

806030

IMB4
Importin subunit beta-4

1

6

High-throughput

0.445

High

806032

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

806036

MPG1
Mannose-1-phosphate guanyltransferase

1

2

High-throughput

0.445

High

806041

DPH4
Diphthamide biosynthesis protein 4

1

5

High-throughput

0.445

High

548695

RNA1
Ran GTPase-activating protein 1

1

1

High-throughput

0.439

High

758089

CASP
Protein CASP

1

17

High-throughput

0.439

High

804889

LAM4
Membrane-anchored lipid-binding protein LAM4

1

1

High-throughput

0.439

High

806039

GEA1
ARF guanine-nucleotide exchange factor 1

1

2

High-throughput

0.439

High

806043

SGM1
Protein SGM1

1

13

High-throughput

0.439

High

806045

KNL1
Outer kinetochore KNL1 complex subunit SPC105

1

1

High-throughput

0.439

High

806054

FCP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

2

High-throughput

0.439

High

806056

SNX41
Sorting nexin-41

1

2

High-throughput

0.439

High

806061

ERP3
Protein ERP3

1

1

High-throughput

0.439

High

806062

CAF1A
Chromatin assembly factor 1 subunit A

1

1

High-throughput

0.439

High

707053

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

806022

TEM1
Protein TEM1

1

1

Small-scale

0.437

High

806033

MLP2
Protein MLP2

1

16

High-throughput

0.437

High

577126

SEC63
Protein translocation protein SEC63

1

4

High-throughput

0.407

High

550578

SST2
Protein SST2

4

0

Small-scale

0.357

High

725964

SWC3
SWR1-complex protein 3

2

0

High-throughput

0.310

High

806028

TOG1
Transcription factor TOG1

1

0

High-throughput

0.269

Low

806059

HDA3
HDA1 complex subunit 3

1

0

High-throughput

0.269

Low

806042

CAF17
Iron-sulfur cluster assembly factor IBA57, mitochondrial

1

0

High-throughput

0.265

Low

806051

STD1
Protein STD1

1

0

High-throughput

0.265

Low

806053

YM46
Uncharacterized protein YMR181C

1

0

High-throughput

0.265

Low

550655

SIR4
Regulatory protein SIR4

1

0

High-throughput

0.251

Low

677751

STP22
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease

1

0

High-throughput

0.251

Low

678272

ARE1
Sterol O-acyltransferase 1

1

0

High-throughput

0.251

Low

806037

GZF3
Protein GZF3

1

0

High-throughput

0.251

Low

806063

MPD2
Protein disulfide isomerase MPD2

1

0

High-throughput

0.251

Low

594360

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

806046

PIB2
Glutamine sensor PIB2

1

0

Small-scale

0.249

Low

806055

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

806052

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025