Interactor 1: NOS1 (P29475)
Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)
Gene: NOS1

Interactor 2: NOS1 (P29475)
Nitric oxide synthase 1 (EC 1.14.13.39) (Constitutive NOS) (NC-NOS) (NOS type I) (Neuronal NOS) (N-NOS) (nNOS) (Nitric oxide synthase, brain) (bNOS) (Peptidyl-cysteine S-nitrosylase NOS1)
Gene: NOS1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.57 1.00 0.757

The method score is based on:

Property Details
Experiments 8995432, 19364813
Identification Methods two hybrid, comigration in gel electrophoresis
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains FAD_binding_1~FAD_binding_1, FAD_binding_1~Flavodoxin_1, FAD_binding_1~NAD_binding_1, Flavodoxin_1~Flavodoxin_1, Flavodoxin_1~NAD_binding_1, NAD_binding_1~NAD_binding_1, NO_synthase~NO_synthase, PDZ~PDZ
Common GO terms GO:0001666 - response to hypoxia
GO:0001917 - photoreceptor inner segment
GO:0002028 - regulation of sodium ion transport
GO:0004517 - nitric-oxide synthase activity
GO:0005246 - calcium channel regulator activity
and 61 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1434
Hs

1 1434
+ Hs
+ Bt
+ Hs
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Ec

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Last updated: 15 Jul 2024