Protein: RL1A
Large ribosomal subunit protein uL1A (60S ribosomal protein L1-A) (L10a)

Gene: RL1A, RPL1A
Organism: Saccharomyces cerevisiae S288C
Interactions: 196
UniProt ID: P0CX43

Gene Ontology (top 5):
GO:0000055 - ribosomal large subunit export from nucleus
GO:0002181 - cytoplasmic translation
GO:0003723 - RNA binding
GO:0003735 - structural constituent of ribosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

513533

LSG1
Large subunit GTPase 1

4

4

Small-scale

0.867

High

513561

HAS1
ATP-dependent RNA helicase HAS1

3

16

High-throughput

0.827

High

513437

RL1A
Large ribosomal subunit protein uL1A

2

6

High-throughput

0.754

High

513465

SPB4
ATP-dependent rRNA helicase SPB4

2

12

High-throughput

0.754

High

513488

MAK5
ATP-dependent RNA helicase MAK5

2

13

High-throughput

0.754

High

427091

RLA0
Large ribosomal subunit protein uL10

4

6

Small-scale

0.676

High

513538

PESC
Pescadillo homolog

3

1

Small-scale

0.640

High

154119

RL36B
Large ribosomal subunit protein eL36B

1

4

High-throughput

0.618

High

434123

RL36A
Large ribosomal subunit protein eL36A

1

4

High-throughput

0.618

High

513454

RL8A
Large ribosomal subunit protein eL8A

1

5

High-throughput

0.618

High

513470

RL8B
Large ribosomal subunit protein eL8B

1

5

High-throughput

0.618

High

513495

CIC1
Proteasome-interacting protein CIC1

1

1

High-throughput

0.618

High

513558

RLI1
Translation initiation factor RLI1

1

3

High-throughput

0.618

High

513570

DHR1
Probable ATP-dependent RNA helicase DHR1

1

7

High-throughput

0.618

High

513595

DBP10
ATP-dependent RNA helicase DBP10

1

12

High-throughput

0.618

High

513602

RL11B
Large ribosomal subunit protein uL5B

1

3

High-throughput

0.618

High

513461

SIS1
Protein SIS1

2

4

High-throughput

0.601

High

392083

HSP82
ATP-dependent molecular chaperone HSP82

2

5

High-throughput

0.584

High

432454

RL7A
Large ribosomal subunit protein uL30A

2

6

High-throughput

0.584

High

513445

HSP71
Heat shock protein SSA1

2

3

High-throughput

0.584

High

513467

RL16A
Large ribosomal subunit protein uL13A

2

5

High-throughput

0.584

High

513499

NMD3
60S ribosomal export protein NMD3

2

1

High-throughput

0.584

High

513515

RL10
Large ribosomal subunit protein uL16

2

2

High-throughput

0.584

High

513519

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

3

High-throughput

0.584

High

513544

NOP15
Ribosome biogenesis protein 15

2

7

High-throughput

0.584

High

513565

ARX1
Probable metalloprotease ARX1

2

2

Small-scale

0.584

High

513593

RL7B
Large ribosomal subunit protein uL30B

2

6

High-throughput

0.584

High

513600

RL13A
Large ribosomal subunit protein eL13A

2

5

High-throughput

0.584

High

513587

NEW1
[NU+] prion formation protein 1

1

4

Small-scale

0.579

High

513484

RPF2
Ribosome biogenesis protein RPF2

2

5

High-throughput

0.558

High

513453

EF3A
Elongation factor 3A

1

4

High-throughput

0.553

High

513502

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.553

High

513522

MTR4
ATP-dependent RNA helicase DOB1

1

7

High-throughput

0.553

High

513578

HRQ1
ATP-dependent helicase HRQ1

1

7

Small-scale

0.553

High

513464

PWP2
Periodic tryptophan protein 2

2

9

High-throughput

0.533

High

513492

ENP1
Essential nuclear protein 1

2

2

High-throughput

0.533

High

513497

SSF1
Ribosome biogenesis protein SSF1

2

5

Small-scale

0.533

High

513511

DSN1
Kinetochore-associated protein DSN1

2

3

High-throughput

0.533

High

513597

NOP58
Nucleolar protein 58

2

7

Small-scale

0.533

High

513594

RKM5
Ribosomal lysine N-methyltransferase 5

1

0

Small-scale

0.480

High

383062

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.479

High

394144

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.479

High

409671

RL24A
Large ribosomal subunit protein eL24A

1

4

High-throughput

0.479

High

427525

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.479

High

427646

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.479

High

432778

RL9A
Large ribosomal subunit protein uL6A

1

3

High-throughput

0.479

High

432957

RL6B
Large ribosomal subunit protein eL6B

1

2

High-throughput

0.479

High

433121

RL17A
Large ribosomal subunit protein uL22A

1

4

High-throughput

0.479

High

433376

RL26A
Large ribosomal subunit protein uL24A

1

6

High-throughput

0.479

High

434495

RL22A
Large ribosomal subunit protein eL22A

1

1

High-throughput

0.479

High

436284

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

4

High-throughput

0.479

High

438581

SC160
Protein SCP160

1

1

High-throughput

0.479

High

503879

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.479

High

509856

RL40A
Ubiquitin-ribosomal protein eL40A fusion protein [Cleaved into: Ubiquitin; Large ribosomal subunit protein eL40A

1

4

Small-scale

0.479

High

511112

RL20B
Large ribosomal subunit protein eL20B

1

3

High-throughput

0.479

High

511354

RL43B
Large ribosomal subunit protein eL43B

1

2

High-throughput

0.479

High

511528

RL44B
Large ribosomal subunit protein eL42B

1

3

High-throughput

0.479

High

513438

RL2A
Large ribosomal subunit protein uL2A

1

4

High-throughput

0.479

High

513439

RL18B
Large ribosomal subunit protein eL18B

1

2

High-throughput

0.479

High

513440

RL12B
Large ribosomal subunit protein uL11B

1

1

High-throughput

0.479

High

513441

RL19B
Large ribosomal subunit protein eL19

1

2

High-throughput

0.479

High

513442

RL35A
Large ribosomal subunit protein uL29A

1

3

High-throughput

0.479

High

513446

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.479

High

513449

RL3
Large ribosomal subunit protein uL3

1

3

High-throughput

0.479

High

513450

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

513451

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.479

High

513459

RL24B
Large ribosomal subunit protein eL24B

1

4

High-throughput

0.479

High

513463

KRR1
KRR1 small subunit processome component

1

3

High-throughput

0.479

High

513466

RL5
Large ribosomal subunit protein uL18

1

3

High-throughput

0.479

High

513472

ZUO1
Zuotin

1

7

High-throughput

0.479

High

513475

MRT4
Ribosome assembly factor MRT4

1

6

Small-scale

0.479

High

513482

RL14A
Large ribosomal subunit protein eL14A

1

3

High-throughput

0.479

High

513487

GBLP
Small ribosomal subunit protein RACK1

1

11

Small-scale

0.479

High

513493

RL14B
Large ribosomal subunit protein eL14B

1

3

High-throughput

0.479

High

513496

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.479

High

513500

RIX1
Pre-rRNA-processing protein RIX1

1

1

High-throughput

0.479

High

513501

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

513503

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.479

High

513506

RL13B
Large ribosomal subunit protein eL13B

1

5

High-throughput

0.479

High

513509

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.479

High

513512

RLP7
Ribosome biogenesis protein RLP7

1

6

High-throughput

0.479

High

513513

NOP2
25S rRNA

1

5

High-throughput

0.479

High

513514

RL33B
Large ribosomal subunit protein eL33B

1

1

High-throughput

0.479

High

513518

LOC1
60S ribosomal subunit assembly/export protein LOC1

1

1

High-throughput

0.479

High

513520

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

513521

RL17B
Large ribosomal subunit protein uL22B

1

4

High-throughput

0.479

High

513525

RL37A
Large ribosomal subunit protein eL37A

1

1

High-throughput

0.479

High

513526

RL4B
Large ribosomal subunit protein uL4B

1

4

High-throughput

0.479

High

513529

RL9B
Large ribosomal subunit protein uL6B

1

3

High-throughput

0.479

High

513530

RL37B
Large ribosomal subunit protein eL37B

1

1

High-throughput

0.479

High

513535

RL26B
Large ribosomal subunit protein uL24B

1

6

High-throughput

0.479

High

513539

SDA1
Protein SDA1

1

1

High-throughput

0.479

High

513540

BRE5
UBP3-associated protein BRE5

1

7

High-throughput

0.479

High

513542

NOP13
Nucleolar protein 13

1

5

High-throughput

0.479

High

513545

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

513548

RL22B
Large ribosomal subunit protein eL22B

1

1

High-throughput

0.479

High

513549

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.479

High

513551

AP1M1
AP-1 complex subunit mu-1-I

1

2

High-throughput

0.479

High

513552

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

3

High-throughput

0.479

High

513553

RL6A
Large ribosomal subunit protein eL6A

1

2

High-throughput

0.479

High

513555

RL21A
Large ribosomal subunit protein eL21A

1

1

High-throughput

0.479

High

513556

XRN2
5'-3' exoribonuclease 2

1

5

High-throughput

0.479

High

513560

GCN5
Histone acetyltransferase GCN5

1

4

High-throughput

0.479

High

513572

VMS1
tRNA endonuclease VMS1

1

1

High-throughput

0.479

High

513576

RRP5
rRNA biogenesis protein RRP5

1

8

High-throughput

0.479

High

513581

NOC4
Nucleolar complex protein 4

1

7

High-throughput

0.479

High

513583

RLP24
Ribosome biogenesis protein RLP24

1

4

Small-scale

0.479

High

513591

CHS5
Chitin biosynthesis protein CHS5

1

3

High-throughput

0.479

High

513599

RL21B
Large ribosomal subunit protein eL21B

1

1

High-throughput

0.479

High

513601

RRP12
Ribosomal RNA-processing protein 12

1

3

High-throughput

0.479

High

434221

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.458

High

481945

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.458

High

513443

RS32B
Small ribosomal subunit protein eS32B

1

0

High-throughput

0.458

High

513490

GID4
GID complex substrate-recognition subunit 4

1

0

High-throughput

0.458

High

513531

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

1

0

High-throughput

0.458

High

513534

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.458

High

513575

LTN1
E3 ubiquitin-protein ligase listerin

1

0

Small-scale

0.458

High

513585

MCA1
Metacaspase-1

1

0

High-throughput

0.458

High

513588

TMA46
Translation machinery-associated protein 46

1

0

High-throughput

0.458

High

513444

SSBP1
Single-stranded nucleic acid-binding protein

1

6

High-throughput

0.457

High

513590

RTK1
Probable serine/threonine-protein kinase RTK1

1

3

High-throughput

0.457

High

513455

SRP54
Signal recognition particle subunit SRP54

1

2

High-throughput

0.445

High

513498

RPF1
Ribosome production factor 1

1

6

High-throughput

0.445

High

513505

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

513589

NOP53
Ribosome biogenesis protein NOP53

1

4

Small-scale

0.445

High

513554

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.439

High

364262

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.437

High

401836

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

High-throughput

0.437

High

448613

SNF1
Carbon catabolite-derepressing protein kinase

1

2

Small-scale

0.437

High

513452

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.437

High

513460

NAP1
Nucleosome assembly protein

1

2

High-throughput

0.437

High

513468

URA7
CTP synthase 1

1

1

High-throughput

0.437

High

513469

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

513471

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

1

High-throughput

0.437

High

513473

SPT16
FACT complex subunit SPT16

1

2

Small-scale

0.437

High

513474

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

513476

PRS6A
26S proteasome regulatory subunit 6A

1

3

High-throughput

0.437

High

513477

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.437

High

513478

IXR1
Intrastrand cross-link recognition protein

1

6

Small-scale

0.437

High

513479

URB1
Nucleolar pre-ribosomal-associated protein 1

1

2

High-throughput

0.437

High

513489

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

5

High-throughput

0.437

High

513510

DOT5
Peroxiredoxin DOT5

1

1

High-throughput

0.437

High

513516

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.437

High

513517

OTU1
Ubiquitin thioesterase OTU1

1

3

High-throughput

0.437

High

513527

IMDH4
Inosine-5'-monophosphate dehydrogenase 4

1

1

High-throughput

0.437

High

513528

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.437

High

513532

NSA1
Ribosome biogenesis protein NSA1

1

2

Small-scale

0.437

High

513536

EIF2A
Eukaryotic translation initiation factor 2A

1

1

Small-scale

0.437

High

513541

GIS2
Zinc finger protein GIS2

1

5

High-throughput

0.437

High

513543

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.437

High

513547

ORC1
Origin recognition complex subunit 1

1

1

High-throughput

0.437

High

513550

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

513557

HOS3
Histone deacetylase HOS3

1

6

High-throughput

0.437

High

513559

TOM1
E3 ubiquitin-protein ligase TOM1

1

4

High-throughput

0.437

High

513567

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.437

High

513568

CTK1
CTD kinase subunit alpha

1

3

High-throughput

0.437

High

513569

RRP17
Ribosomal RNA-processing protein 17

1

1

High-throughput

0.437

High

513571

UTP15
U3 small nucleolar RNA-associated protein 15

1

10

High-throughput

0.437

High

513573

PUF6
Pumilio homology domain family member 6

1

4

High-throughput

0.437

High

513574

UTP14
U3 small nucleolar RNA-associated protein 14

1

3

High-throughput

0.437

High

513579

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

513580

JIP5
WD repeat-containing protein JIP5

1

10

High-throughput

0.437

High

513582

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

513584

SGO1
Shugoshin

1

1

High-throughput

0.437

High

513586

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

513592

MAK21
Ribosome biogenesis protein MAK21

1

7

High-throughput

0.437

High

513596

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.437

High

513598

CMR1
DNA damage-binding protein CMR1

1

6

High-throughput

0.437

High

513603

SUS1
SAGA complex subunit SUS1

1

1

High-throughput

0.437

High

513456

MAK11
Protein MAK11

1

9

Small-scale

0.407

High

513447

CAF20
Cap-associated protein CAF20

2

0

Small-scale

0.305

High

365784

KTHY
Thymidylate kinase

1

0

High-throughput

0.249

Low

513448

STE12
Protein STE12

1

0

Small-scale

0.249

Low

513457

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

High-throughput

0.249

Low

513458

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

513462

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.249

Low

513480

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.249

Low

513481

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

513483

LAS1
Protein LAS1

1

0

Small-scale

0.249

Low

513485

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.249

Low

513486

APE3
Aminopeptidase Y

1

0

High-throughput

0.249

Low

513491

YB47
Uncharacterized protein YBR197C

1

0

High-throughput

0.249

Low

513494

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

513504

YEN1
Holliday junction resolvase YEN1

1

0

High-throughput

0.249

Low

513507

TM108
Protein TMA108

1

0

High-throughput

0.249

Low

513508

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.249

Low

513523

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

513524

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

513537

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.249

Low

513546

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

513562

TCB3
Tricalbin-3

1

0

High-throughput

0.249

Low

513563

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.249

Low

513564

RIFK
Riboflavin kinase

1

0

High-throughput

0.249

Low

513566

FIN1
Filament protein FIN1

1

0

Small-scale

0.249

Low

513577

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025