HitPredict

Interactor 1: NOS2 (P29477)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Inducible NO synthase) (Inducible NOS) (iNOS) (Macrophage NOS) (MAC-NOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Interactor 2: RAC2 (Q05144)
Ras-related C3 botulinum toxin substrate 2 (Protein EN-7) (p21-Rac2)
Gene: RAC2

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	11457725
Identification Methods	two hybrid, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1144 Mm			1 192
+	Mm
		667784 NOS2_MOUSE (1-1144): 0: 1808: 100.00		RAC1_MOUSE (1-192): 8.27e-85: 250: 91.67
+	Hs
		718483 NOS2_HUMAN (1-1144): 0: 1775: 80.78		RAC1_HUMAN (1-192): 8.27e-85: 250: 91.67
+	Hs
		545231 NOS2_HUMAN (1-1144): 0: 1775: 80.78		RAC2_HUMAN (1-192): 2.35e-82: 243: 98.96
+	Hs
		560186 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC1_HUMAN (1-192): 8.27e-85: 250: 91.67
+	Hs
		545195 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC2_HUMAN (1-192): 2.35e-82: 243: 98.96
+	Hs
		560181 NCPR_HUMAN (496-1122): 0: 737: 29.06		RAC3_HUMAN (1-191): 5.68e-79: 235: 88.48
+	Hs
		560188 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOG_HUMAN (1-192): 9.49e-79: 234: 71.35
+	Hs
		560182 NCPR_HUMAN (496-1122): 0: 737: 29.06		CDC42_HUMAN (1-192): 2.53e-77: 231: 69.27
+	Hs
		560184 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOA_HUMAN (5-192): 7.11e-76: 227: 54.26
+	Hs
		436146 NCPR_HUMAN (496-1122): 0: 737: 29.06		RHOC_HUMAN (5-192): 7.5e-74: 222: 54.79