HitPredict

Interactor 1: SPB3 (P29508)
Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1)
Gene: SERPINB3

Interactor 2: DD19B (Q9UMR2)
ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B)
Gene: DDX19B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26186194, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 390 Hs			1 479
+	Hs
		820405 SPB4_HUMAN (1-390): 6.25e-177: 499: 91.80		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		397078 PAI2_HUMAN (1-390): 6.23e-155: 444: 41.73		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		675663 ILEU_HUMAN (1-390): 1.95e-150: 431: 46.72		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		344350 AACT_HUMAN (4-390): 7.56e-142: 411: 32.82		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		344252 A1AT_HUMAN (2-390): 4.63e-140: 406: 32.82		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		271900 SPB7_HUMAN (1-390): 3.38e-140: 405: 39.80		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		397045 PAI2_HUMAN (1-390): 6.23e-155: 444: 41.73		DDX42_HUMAN (1-476): 8.35e-120: 374: 25.56
+	Hs
		738821 SPB5_HUMAN (1-390): 4.3e-132: 384: 34.34		DD19B_HUMAN (1-479): 2.69e-141: 416: 100.00
+	Hs
		134171 SPB12_HUMAN (1-390): 1.23e-145: 420: 46.55		DDX3X_HUMAN (23-476): 7.98e-122: 372: 25.26