Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 27903803, 29599493, 10669754, 32296183, 34795231, 36880596, 16778193, 9671498, 9230084, 16540467, 22773875, 22493164, 12438698, unassigned1304, 20211142, 9294197
Identification Methods enzymatic study, affinity chromatography technology, x-ray crystallography, pull down, far western blotting, two hybrid, proximity labelling technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-B_box~zf-B_box, zf-B_box~zf-C3HC4
Common GO terms GO:0000781 - chromosome, telomeric region
GO:0001666 - response to hypoxia
GO:0002230 - positive regulation of defense response to virus by host
GO:0003677 - DNA binding
GO:0003713 - transcription coactivator activity
and 82 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 15 Jul 2024