Interactor 1: ERG6 (P25087)
Sterol 24-C-methyltransferase ERG6 (SCMT) (EC 2.1.1.41) (Delta(24)-sterol C-methyltransferase ERG6) (Ergosterol biosynthetic protein 6)
Gene: ERG6

Interactor 2: ERG4 (P25340)
Delta(24(24(1)))-sterol reductase ERG4 (EC 1.3.1.71) (C-24(28) sterol reductase ERG4) (Ergosterol biosynthetic protein 4) (Sterol Delta(24(28))-reductase ERG4)
Gene: ERG4

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 16300994
Identification Methods protein complementation assay, ubiquitin reconstruction
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0006696 - ergosterol biosynthetic process
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 383
Sc

1 473
+ Sc

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Last updated: 11Aug2025