Interactor 1: AL4A1 (P30038)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)
Gene: ALDH4A1

Interactor 2: AL4A1 (P30038)
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (P5C dehydrogenase) (EC 1.2.1.88) (Aldehyde dehydrogenase family 4 member A1) (L-glutamate gamma-semialdehyde dehydrogenase)
Gene: ALDH4A1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.777

The method score is based on:

Property Details
Experiments 24502590, 22516612
Identification Methods x-ray crystallography, cosedimentation
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Aldedh~Aldedh
Common GO terms GO:0003842 - 1-pyrroline-5-carboxylate dehydrogenase activity
GO:0004029 - aldehyde dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol
and 5 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 563
Hs

1 563
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Sc
+ Hs
+ Sc
+ Dr
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024