Protein: SXM1
Importin beta SMX1 (Suppressor of mRNA export mutant protein 1) (karyopherin-108)

Gene: SXM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 83
UniProt ID: Q04175

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751985

LHP1
La protein homolog

4

3

Small-scale

0.697

High

813719

ECM1
Shuttling pre-60S factor ECM1

4

0

Small-scale

0.658

High

745865

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

20

Small-scale

0.647

High

1037957

NU100
Nucleoporin NUP100/NSP100

3

20

Small-scale

0.640

High

722234

XPO1
Exportin-1

1

10

High-throughput

0.618

High

779342

CENPA
Histone H3-like centromeric protein CSE4

1

7

High-throughput

0.618

High

796122

IMB2
Importin subunit beta-2

1

11

High-throughput

0.618

High

897500

UBC9
SUMO-conjugating enzyme UBC9

1

7

High-throughput

0.618

High

503432

RL11A
Large ribosomal subunit protein uL5A

2

2

Small-scale

0.611

High

546163

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.601

High

689279

RL16B
Large ribosomal subunit protein uL13B

2

0

Small-scale

0.585

High

580014

HSC82
ATP-dependent molecular chaperone HSC82

2

6

High-throughput

0.584

High

755168

GCN1
eIF-2-alpha kinase activator GCN1

2

7

High-throughput

0.571

High

782097

RL1D1
Ribosome biogenesis protein UTP30

1

1

High-throughput

0.536

High

410326

RL25
Large ribosomal subunit protein uL23

1

5

Small-scale

0.515

High

577345

NSP1
Nucleoporin NSP1

1

20

Small-scale

0.515

High

634279

NUP1
Nucleoporin NUP1

1

20

Small-scale

0.515

High

825178

NU159
Nucleoporin NUP159

1

20

Small-scale

0.515

High

672342

RV161
Reduced viability upon starvation protein 161

1

1

Small-scale

0.508

High

836554

T2FB
Transcription initiation factor IIF subunit beta

1

3

Small-scale

0.501

High

1045091

ASR1
Alcohol-sensitive RING finger protein 1

1

2

Small-scale

0.501

High

1045096

YP015
Zinc finger protein YPR015C

1

20

High-throughput

0.489

High

1044290

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.486

High

1045092

NBA1
Protein NBA1

1

0

High-throughput

0.486

High

403648

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.480

High

393282

HSP82
ATP-dependent molecular chaperone HSP82

1

6

High-throughput

0.479

High

435343

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

504404

RL31A
Large ribosomal subunit protein eL31A

1

2

Small-scale

0.479

High

518385

IF4A
ATP-dependent RNA helicase eIF4A

1

6

High-throughput

0.479

High

639063

VPS1
Vacuolar protein sorting-associated protein 1

1

3

High-throughput

0.479

High

670333

NAP1
Nucleosome assembly protein

1

5

Small-scale

0.479

High

671089

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

708091

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

727299

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

734727

IMB3
Importin subunit beta-3

1

12

High-throughput

0.479

High

795197

NU170
Nucleoporin NUP170

1

6

High-throughput

0.479

High

817947

IMB4
Importin subunit beta-4

1

12

High-throughput

0.479

High

825302

MOB1
DBF2 kinase activator protein MOB1

1

5

High-throughput

0.479

High

825905

RL34B
Large ribosomal subunit protein eL34B

1

1

Small-scale

0.479

High

850193

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

2

High-throughput

0.479

High

877981

NUP57
Nucleoporin NUP57

1

20

High-throughput

0.479

High

1018155

RL34A
Large ribosomal subunit protein eL34A

1

1

Small-scale

0.479

High

1037984

NU116
Nucleoporin NUP116/NSP116

1

20

High-throughput

0.479

High

1045087

SIZ1
E3 SUMO-protein ligase SIZ1

1

3

High-throughput

0.479

High

1045088

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

1045090

IMB1
Importin subunit beta-1

1

11

High-throughput

0.479

High

1045093

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.479

High

1045095

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.479

High

1045097

RL11B
Large ribosomal subunit protein uL5B

1

2

Small-scale

0.479

High

455248

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

647211

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

702313

MGLL
Monoglyceride lipase

1

0

High-throughput

0.458

High

735146

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

365180

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.445

High

394881

EF1A
Elongation factor 1-alpha

1

4

High-throughput

0.445

High

453779

PYR1
Multifunctional protein URA2

1

4

High-throughput

0.445

High

525055

HSP71
Heat shock protein SSA1

1

11

High-throughput

0.445

High

527602

HSP72
Heat shock protein SSA2

1

11

High-throughput

0.445

High

592487

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.445

High

676320

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

816386

HSP7E
Heat shock protein SSC3, mitochondrial

1

9

High-throughput

0.445

High

826483

DJP1
DnaJ-like protein 1

1

4

High-throughput

0.445

High

836884

MPG1
Mannose-1-phosphate guanyltransferase

1

4

High-throughput

0.445

High

858063

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.445

High

922672

HST4
NAD-dependent histone deacetylase HST4

1

7

High-throughput

0.445

High

1044140

GIS1
Transcriptional activator/repressor GIS1

1

12

High-throughput

0.445

High

564762

ATC1
Calcium-transporting ATPase 1

1

4

High-throughput

0.437

High

734786

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

1

High-throughput

0.437

High

751117

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

2

High-throughput

0.437

High

751715

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

3

High-throughput

0.437

High

816212

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

3

High-throughput

0.437

High

818715

GMT1
GDP-mannose transporter 1

1

5

High-throughput

0.437

High

850938

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

High-throughput

0.437

High

1045089

SGPL
Sphingosine-1-phosphate lyase

1

2

High-throughput

0.437

High

1045094

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

651986

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.426

High

825477

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

4

High-throughput

0.407

High

915411

NBP1
NAP1-binding protein

1

0

Small-scale

0.279

Low

917471

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.279

Low

528634

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

High-throughput

0.249

Low

822335

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.249

Low

1025029

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

918384

TAM41
Phosphatidate cytidylyltransferase, mitochondrial

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025