Interactor 1: GFRP (P30047)
GTP cyclohydrolase 1 feedback regulatory protein (GFRP) (GTP cyclohydrolase I feedback regulatory protein) (p35)
Gene: GCHFR

Interactor 2: GCH1 (P30793)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
Gene: GCH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.43 1.00 0.656

The method score is based on:

Property Details
Experiments 16696853
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GFRP~GTP_cyclohydroI
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0031965 - nuclear membrane
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 84
Hs

1 250
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024