HitPredict

Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 1.00 0.820

The method score is based on:

Property Details
Experiments 37071682, 21988832, 25914057
Identification Methods cross-linking study, two hybrid, 3D electron microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains 1-cysPrx_C~1-cysPrx_C, 1-cysPrx_C~AhpC-TSA, AhpC-TSA~AhpC-TSA
Common GO terms GO:0001893 - maternal placenta development
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
and 24 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 256
Hs

1 256
+ Bt
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Os
+ Hs
+ Mm
+ At

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Last updated: 15 Jul 2024