Protein: IML1
Vacuolar membrane-associated protein IML1 (Increased minichromosome loss protein 1) (SEH-associated protein 1)

Gene: IML1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P47170

Gene Ontology (top 5):
GO:0000329 - fungal-type vacuole membrane
GO:0005096 - GTPase activator activity
GO:0005774 - vacuolar membrane
GO:0006995 - cellular response to nitrogen starvation
GO:0010508 - positive regulation of autophagy

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814928

NPR2
Nitrogen permease regulator 2

4

3

Small-scale

0.878

High

866232

SEH1
Nucleoporin SEH1

4

12

Small-scale

0.878

High

866244

WDR59
Maintenance of telomere capping protein 5

3

12

Small-scale

0.834

High

866246

SEC13
Protein transport protein SEC13

3

8

Small-scale

0.834

High

866250

RTC1
Restriction of telomere capping protein 1

3

13

Small-scale

0.834

High

866240

2ABA
Protein phosphatase PP2A regulatory subunit B

2

1

High-throughput

0.811

High

866241

RAGAB
GTP-binding protein GTR1

1

4

Small-scale

0.740

High

803212

NPR3
Nitrogen permease regulator 3

4

1

Small-scale

0.680

High

794713

SEA4
SEH-associated protein 4

3

3

Small-scale

0.646

High

866228

IML1
Vacuolar membrane-associated protein IML1

1

14

High-throughput

0.575

High

815982

VAC8
Vacuolar protein 8

1

6

High-throughput

0.541

High

866239

CTR9
RNA polymerase-associated protein CTR9

2

1

High-throughput

0.537

High

392990

HSP82
ATP-dependent molecular chaperone HSP82

2

1

High-throughput

0.521

High

579692

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.521

High

416893

CDC25
Cell division control protein 25

1

0

High-throughput

0.517

High

792418

BOI1
BEM1-interacting protein 1

1

4

High-throughput

0.494

High

816033

BOI2
BEM1-interacting protein 2

1

3

High-throughput

0.494

High

560727

KIN2
Serine/threonine-protein kinase KIN2

1

5

High-throughput

0.489

High

642420

MCK1
Protein kinase MCK1

1

1

High-throughput

0.489

High

722073

XPO1
Exportin-1

1

5

High-throughput

0.489

High

866234

FMP48
Probable serine/threonine-protein kinase FMP48

1

3

High-throughput

0.489

High

584376

GCN2
eIF-2-alpha kinase GCN2

1

2

High-throughput

0.479

High

866248

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

866230

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

High-throughput

0.470

High

866238

LSM3
LSM complex subunit LSM3

1

2

High-throughput

0.464

High

524454

HSP71
Heat shock protein SSA1

1

3

High-throughput

0.445

High

527085

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

676135

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

806312

KOG1
Target of rapamycin complex 1 subunit KOG1

1

5

High-throughput

0.445

High

647801

RFA1
Replication factor A protein 1

1

5

Small-scale

0.439

High

475128

CYAA
Adenylate cyclase

1

3

High-throughput

0.437

High

815168

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

3

High-throughput

0.437

High

653876

HSP12
12 kDa heat shock protein

1

0

High-throughput

0.426

High

866243

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

545452

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.407

High

670892

SIS1
Protein SIS1

1

1

High-throughput

0.407

High

727162

HS104
Heat shock protein 104

1

1

High-throughput

0.407

High

741915

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.407

High

752470

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

804277

SSZ1
Ribosome-associated complex subunit SSZ1

1

2

High-throughput

0.407

High

816289

HSP7E
Heat shock protein SSC3, mitochondrial

1

4

High-throughput

0.407

High

819180

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.407

High

826451

DJP1
DnaJ-like protein 1

1

1

High-throughput

0.407

High

866235

JJJ1
J protein JJJ1

1

1

High-throughput

0.407

High

866237

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.407

High

866251

CDC53
Cell division control protein 53

1

8

High-throughput

0.407

High

866252

HSP42
Heat shock protein 42

1

2

High-throughput

0.407

High

740985

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

3

0

High-throughput

0.335

High

382196

H4
Histone H4

2

0

High-throughput

0.324

High

792618

RM16
Large ribosomal subunit protein uL16m

2

0

High-throughput

0.324

High

866242

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

2

0

High-throughput

0.324

High

866249

CYK3
Cytokinesis protein 3

1

0

High-throughput

0.282

High

866247

COG8
Conserved oligomeric Golgi complex subunit 8

1

0

High-throughput

0.279

Low

818016

LSM4
LSM complex subunit LSM4

1

0

High-throughput

0.265

Low

818466

LSM5
LSM complex subunit LSM5

1

0

High-throughput

0.265

Low

594450

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

605391

RTPT
Small ribosomal subunit protein mS26

1

0

High-throughput

0.249

Low

632185

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.249

Low

679842

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

707550

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

747934

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

802795

OSH3
Oxysterol-binding protein homolog 3

1

0

High-throughput

0.249

Low

826386

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.249

Low

866233

MDS3
Negative regulator of sporulation MDS3

1

0

High-throughput

0.249

Low

866245

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.249

Low

577172

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

816721

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low

863636

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

866229

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

866231

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.232

Low

866236

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025