HitPredict

Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 832
+	Hs
		671019 PRDX3_HUMAN (1-256): 3.48e-122: 349: 100.00		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		670682 PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		670764 PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		965096 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		989422 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39