HitPredict

Interactor 1: PRDX3 (P30048)
Thioredoxin-dependent peroxide reductase, mitochondrial (EC 1.11.1.24) (Antioxidant protein 1) (AOP-1) (HBC189) (Peroxiredoxin III) (Prx-III) (Peroxiredoxin-3) (Protein MER5 homolog) (Thioredoxin-dependent peroxiredoxin 3)
Gene: PRDX3

Interactor 2: DDRGK (Q96HY6)
DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1)
Gene: DDRGK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32807901
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation GO:0043066 - negative regulation of apoptotic process GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 314
+	Hs
		1026747 PRDX4_HUMAN (35-255): 3.38e-103: 302: 58.82		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		685747 PRDX2_HUMAN (58-255): 2.07e-104: 302: 63.13		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		989366 PRDX1_HUMAN (63-253): 1.5e-100: 293: 63.54		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00
+	Hs
		670750 PRDX6_HUMAN (63-254): 3.4e-68: 211: 25.25		DDRGK_HUMAN (1-314): 5.29e-64: 206: 100.00