HitPredict

Interactor 1: PDIA3 (P30101)
Protein disulfide-isomerase A3 (EC 5.3.4.1) (58 kDa glucose-regulated protein) (58 kDa microsomal protein) (p58) (Disulfide isomerase ER-60) (Endoplasmic reticulum resident protein 57) (ER protein 57) (ERp57) (Endoplasmic reticulum resident protein 60) (ER protein 60) (ERp60)
Gene: PDIA3

Interactor 2: DNJB9 (Q9UBS3)
DnaJ homolog subfamily B member 9 (Endoplasmic reticulum DNA J domain-containing protein 4) (ER-resident protein ERdj4) (ERdj4) (Microvascular endothelial differentiation gene 1 protein) (Mdg-1)
Gene: DNAJB9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~Thioredoxin
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0034976 - response to endoplasmic reticulum stress GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 223
+	Hs
		636249 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DNJB1_HUMAN (24-212): 4.11e-48: 162: 28.14
+	Hs
		671877 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		671948 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		671939 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		671964 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		671862 PDIA3_HUMAN (1-505): 6.41e-165: 478: 100.00		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		423379 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		423304 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		423380 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		423372 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		423398 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		423286 PDIA1_HUMAN (3-482): 1.23e-118: 359: 33.68		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		532010 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DNJB9_HUMAN (1-223): 5.42e-72: 220: 100.00
+	Hs
		1220492 DJC10_HUMAN (27-244): 3.4e-31: 129: 17.39		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		531914 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DJB14_HUMAN (10-174): 1.47e-46: 159: 31.74
+	Hs
		532011 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DJB11_HUMAN (4-109): 1.65e-44: 154: 42.06
+	Hs
		532000 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DJB12_HUMAN (2-177): 4.03e-44: 153: 29.28
+	Hs
		532027 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DJC16_HUMAN (10-135): 4.26e-41: 150: 36.15
+	Hs
		531897 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DJC10_HUMAN (6-219): 3.47e-40: 148: 25.33
+	Hs
		532013 PDIA4_HUMAN (376-505): 1.13e-23: 106: 32.84		DNJ5B_HUMAN (19-203): 1.4e-43: 146: 27.27