Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.792

The method score is based on:

Property Details
Experiments 22569334, 16044149
Identification Methods enzymatic study, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT~Pkinase, HEAT_2~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0015630 - microtubule cytoskeleton
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 589
Hs

1 480
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024