Interactor 1: ERG4 (P25340)
Delta(24(24(1)))-sterol reductase ERG4 (EC 1.3.1.71) (C-24(28) sterol reductase ERG4) (Ergosterol biosynthetic protein 4) (Sterol Delta(24(28))-reductase ERG4)
Gene: ERG4
Interactor 2: ERG4 (P25340)
Delta(24(24(1)))-sterol reductase ERG4 (EC 1.3.1.71) (C-24(28) sterol reductase ERG4) (Ergosterol biosynthetic protein 4) (Sterol Delta(24(28))-reductase ERG4)
Gene: ERG4
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16300994 |
| Identification Methods | protein complementation assay, ubiquitin reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | ERG4_ERG24~ERG4_ERG24 |
| Common GO terms | GO:0000246 - Delta24(24-1) sterol reductase activity GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0006696 - ergosterol biosynthetic process GO:0050614 - Delta24-sterol reductase activity |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
