HitPredict

Interactor 1: 2AAB (P30154)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform (PP2A subunit A isoform PR65-beta) (PP2A subunit A isoform R1-beta)
Gene: PPP2R1B

Interactor 2: STRN3 (Q13033)
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)
Gene: STRN3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.930

Property	Details
Experiments	24366813, 26496610, 33961781, 17540176, 18782753
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HEAT_2~Striatin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 601 Hs			1 797
+	Hs
		672100 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		STRN3_HUMAN (1-797): 0: 626: 100.00
+	Hs
		215198 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		215199 2AAB_HUMAN (1-601): 8.13e-170: 497: 100.00		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		672317 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		672479 2AAB_HUMAN (1-601): 8.13e-170: 497: 100.00		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		672152 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		Q59GV6_HUMAN (4-708): 1.62e-99: 327: 25.96
+	Hs
		672167 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Dm
		87968 2AAA_DROME (11-590): 7.14e-155: 459: 71.72		D3DML3_DROME (382-797): 1.67e-86: 292: 55.74
+	Dm
		734229 2AAA_DROME (11-590): 7.14e-155: 459: 71.72		Q9VLT9_DROME (468-797): 4.17e-86: 290: 66.36
+	Hs
		672284 2AAA_HUMAN (14-601): 3.9e-172: 503: 86.22		TBL1R_HUMAN (428-663): 1.15e-43: 167: 18.21
+	Hs
		980822 PP4R1_HUMAN (337-595): 6.3e-09: 61.2: 17.78		TLE3_HUMAN (47-796): 1.52e-91: 305: 14.81
+	Hs
		1146684 GCN1_HUMAN (20-600): 6.38e-12: 71: 14.37		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Hs
		155585 TNPO2_HUMAN (37-386): 1.53e-10: 66.4: 15.42		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Hs
		268646 SF3B1_HUMAN (147-580): 4.07e-18: 90.6: 13.84		WDR5_HUMAN (289-613): 1.4e-54: 193: 16.37
+	Hs
		245645 PP4RL_HUMAN (272-485): 1.28e-10: 65.8: 18.81		TBL1X_HUMAN (353-712): 8.84e-57: 206: 13.94
+	Hs
		903400 GCN1_HUMAN (20-600): 6.38e-12: 71: 14.37		WDR5_HUMAN (289-613): 1.4e-54: 193: 16.37
+	Sp
		1303221 2AAA_SCHPO (102-601): 3.34e-48: 179: 19.60		COPA_SCHPO (690-796): 6.95e-09: 61.6: 28.97
+	Hs
		1318184 PP4RL_HUMAN (272-485): 1.28e-10: 65.8: 18.81		TBL1R_HUMAN (428-663): 1.15e-43: 167: 18.21
+	Hs
		209364 SF3B1_HUMAN (147-580): 4.07e-18: 90.6: 13.84		PLRG1_HUMAN (456-620): 1.77e-19: 94.5: 18.00
+	Hs
		268815 SF3B1_HUMAN (147-580): 4.07e-18: 90.6: 13.84		SNR40_HUMAN (525-796): 1.64e-14: 77.8: 23.76