HitPredict

Interactor 1: CCND2 (P30279)
G1/S-specific cyclin-D2
Gene: CCND2

Interactor 2: CDK5 (Q00535)
Cyclin-dependent kinase 5 (EC 2.7.11.1) (Cell division protein kinase 5) (Cyclin-dependent-like kinase 5) (Serine/threonine-protein kinase PSSALRE) (Tau protein kinase II catalytic subunit) (TPKII catalytic subunit)
Gene: CDK5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 25416956, 26186194, 28514442, 27107012, 32296183, 33961781, 26871637, 9422379, 32707033, 23602568, 23455922, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, validated two hybrid, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, pull down, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 289
Hs

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Last updated: 15 Jul 2024