Protein: SIW14
Inositol diphosphatase SIW14 (EC 3.6.1.52) (5-PP-InsP phosphatase) (Inositol pyrophosphate phosphatase SIW14) (Oxidant-induced cell-cycle arrest protein 3) (Synthetic interaction with WHI2 protein 14)

Gene: SIW14
Organism: Saccharomyces cerevisiae S288C
Interactions: 44
UniProt ID: P53965

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007015 - actin filament organization
GO:0016791 - phosphatase activity
GO:0052840 - inositol diphosphate tetrakisphosphate diphosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

898936

OCA1
Putative tyrosine-protein phosphatase OCA1

7

6

High-throughput

0.970

High

925258

OCA2
Tyrosine-protein phosphatase-like protein OCA2

6

6

Small-scale

0.940

High

673071

OCA4
Protein OCA4

2

10

High-throughput

0.789

High

925341

OCA6
Putative tyrosine-protein phosphatase OCA6

1

6

High-throughput

0.618

High

803188

OCA5
Oxidant-induced cell-cycle arrest protein 5

2

3

High-throughput

0.611

High

545863

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.601

High

722163

XPO1
Exportin-1

1

3

High-throughput

0.536

High

925338

EMI2
Putative glucokinase-2

1

2

High-throughput

0.536

High

416466

HXKA
Hexokinase-1

1

2

High-throughput

0.500

High

607776

HXKG
Glucokinase-1

1

2

High-throughput

0.500

High

925339

CORO
Coronin-like protein

1

0

High-throughput

0.493

High

779691

YPT53
GTP-binding protein YPT53

1

0

High-throughput

0.486

High

864123

LSM1
LSM1-LSM7 complex subunit LSM1

1

0

High-throughput

0.486

High

408337

GAL1
Galactokinase

1

0

High-throughput

0.479

High

555124

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.479

High

746300

UGPA1
UTP--glucose-1-phosphate uridylyltransferase

1

0

High-throughput

0.479

High

745832

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

1

High-throughput

0.479

High

925337

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

925340

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.458

High

393151

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.445

High

527396

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

670995

SIS1
Protein SIS1

1

2

High-throughput

0.445

High

676240

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

742151

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

819467

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

836834

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

924977

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.445

High

707866

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

365148

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

386819

TBB
Tubulin beta chain

1

0

High-throughput

0.426

High

394800

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

453734

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

486282

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

592424

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

734173

EF2
Elongation factor 2

1

0

High-throughput

0.426

High

802675

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.426

High

804365

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

817922

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

921399

MPA43
Protein MPA43

1

0

High-throughput

0.426

High

808970

HXT6
High-affinity hexose transporter HXT6

1

0

High-throughput

0.279

Low

925336

ACT
Actin

1

0

High-throughput

0.261

Low

575494

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

810867

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

849542

GCN20
Protein GCN20

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025