Interactor 1: CDK4 (P30285)
Cyclin-dependent kinase 4 (EC 2.7.11.22) (CRK3) (Cell division protein kinase 4) (PSK-J3)
Gene: CDK4

Interactor 2: CDN2A (P51480)
Cyclin-dependent kinase inhibitor 2A (Cyclin-dependent kinase 4 inhibitor A) (CDK4I) (p16-INK4a) (p16-INK4)
Gene: Cdkn2a

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 17713536
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Pkinase, Ank_2~Pkinase
Common GO terms GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0009410 - response to xenobiotic stimulus
GO:0010468 - regulation of gene expression
GO:0043065 - positive regulation of apoptotic process
and 1 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 303
Mm

1 168
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024