HitPredict

Interactor 1: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Interactor 2: B2MG (P61769)
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]
Gene: B2M

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.847

The method score is based on:

Property Details
Experiments 26186194, 33961781, 27649529
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, surface plasmon resonance
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I
Common GO terms GO:0000139 - Golgi membrane
GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0005615 - extracellular space
GO:0005765 - lysosomal membrane
GO:0005783 - endoplasmic reticulum
and 9 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 346
Hs

1 119
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024