HitPredict

Interactor 1: HLAF (P30511)
HLA class I histocompatibility antigen, alpha chain F (CDA12) (HLA F antigen) (Leukocyte antigen F) (MHC class I antigen F)
Gene: HLA-F

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	C1-set~ig, C1-set~LRR_8, MHC_I~ig
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 346 Hs			1 839
+	Hs
		382433 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		488237 HLAC_HUMAN (1-308): 1.76e-147: 422: 80.20		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		382259 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		382306 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		FGFR2_HUMAN (203-838): 1.97e-168: 510: 24.89
+	Hs
		382280 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		382308 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		382268 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		382440 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		DDR2_HUMAN (527-824): 2.05e-70: 250: 43.30
+	Hs
		382393 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		382263 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		382269 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		382560 HLAA_HUMAN (1-345): 1.49e-170: 480: 80.29		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		570320 HLAG_HUMAN (1-335): 9.94e-155: 439: 79.10		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		488193 HLAC_HUMAN (1-308): 1.76e-147: 422: 80.20		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		435507 HLAC_HUMAN (1-308): 1.76e-147: 422: 80.20		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Rn
		544828 Q31255_RAT (1-344): 4.99e-149: 426: 61.21		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		533140 HLAE_HUMAN (17-330): 2.38e-143: 411: 73.57		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Rn
		64757 A7LNF8_RAT (22-328): 1.54e-134: 387: 61.02		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		169158 HLAB_HUMAN (1-345): 2.86e-153: 436: 79.71		MUSK_HUMAN (209-391): 1.75e-22: 105: 24.60
+	Hs
		169162 HLAC_HUMAN (1-308): 1.76e-147: 422: 80.20		MUSK_HUMAN (209-391): 1.75e-22: 105: 24.60