HitPredict

Interactor 1: V2R (P30518)
Vasopressin V2 receptor (V2R) (AVPR V2) (Antidiuretic hormone receptor) (Renal-type arginine vasopressin receptor)
Gene: AVPR2

Interactor 2: GBB1 (P62873)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (Transducin beta chain 1)
Gene: GNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15782186
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	7tm_1~WD40
Common GO terms	GO:0005886 - plasma membrane GO:0007186 - G protein-coupled receptor signaling pathway GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 371 Hs			1 340
+	Hs
		429007 ADRB2_HUMAN (1-364): 8.97e-80: 252: 18.82		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		429006 ADRB2_HUMAN (1-364): 8.97e-80: 252: 18.82		GBB1_HUMAN (1-340): 7.02e-105: 312: 100.00
+	Hs
		429130 ADRB2_HUMAN (1-364): 8.97e-80: 252: 18.82		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88
+	Rn
		495780 ADRB2_RAT (12-362): 1.69e-78: 248: 18.38		GNB5_RAT (129-340): 1.48e-45: 160: 21.92
+	Hs
		825679 MTR1B_HUMAN (21-340): 1.8e-11: 66.6: 22.46		GBB2_HUMAN (1-340): 1e-105: 314: 90.29
+	Hs
		825746 MTR1B_HUMAN (21-340): 1.8e-11: 66.6: 22.46		GBB4_HUMAN (1-340): 6.23e-105: 312: 90.88