HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35022314
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PK_Tyr_Ser-Thr~SH3_1
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 Hs			1 904
+	Hs
		872639 EPHA4_HUMAN (2-836): 0: 637: 19.40		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		872433 EPHA5_HUMAN (2-812): 0: 622: 20.39		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		1021499 EPHA7_HUMAN (2-837): 0: 621: 19.50		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		674422 UFO_HUMAN (1-894): 0: 780: 100.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		159179 EPHA4_HUMAN (2-836): 0: 637: 19.40		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		159214 EPHA7_HUMAN (2-837): 0: 621: 19.50		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		1049958 EPHA7_HUMAN (2-837): 0: 621: 19.50		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		665600 EPHB2_HUMAN (2-837): 0: 605: 19.58		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		1072518 EPHA7_HUMAN (2-837): 0: 621: 19.50		MPP7_HUMAN (96-459): 7.98e-17: 86.8: 14.80
+	Hs
		665293 EPHA2_HUMAN (3-837): 0: 604: 19.66		DLG5_HUMAN (202-404): 4.58e-19: 95.5: 32.02
+	Rn
		88514 INSR_RAT (276-851): 1.26e-134: 437: 27.83		MPP2_RAT (122-320): 2.19e-13: 76: 15.84
+	Mm
		555008 MET_MOUSE (536-799): 5.47e-66: 243: 45.90		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		441501 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Mm
		710140 FAK1_MOUSE (527-889): 3.59e-57: 215: 34.95		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		601553 FGFR2_HUMAN (27-239): 5.42e-33: 139: 14.46		DLG5_HUMAN (202-404): 4.58e-19: 95.5: 32.02
+	Hs
		159144 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Hs
		169176 MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		507995 FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		609417 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		PALS1_HUMAN (1-397): 1.55e-20: 99.1: 14.74
+	Hs
		609253 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		EM55_HUMAN (161-314): 1.14e-14: 79.5: 14.56