HitPredict

Interactor 1: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	32707033, 23629654
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 303
+	Hs
		213488 UFO_HUMAN (1-894): 0: 780: 100.00		SGTA_HUMAN (3-140): 2.4e-33: 126: 29.71
+	Hs
		411526 INSR_HUMAN (272-851): 1.65e-136: 443: 27.97		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		441587 MET_HUMAN (536-799): 3.42e-66: 243: 45.90		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		981933 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		983691 FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		981923 RON_HUMAN (518-810): 1.36e-56: 214: 40.47		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30
+	Mm
		710144 FAK1_MOUSE (527-889): 3.59e-57: 215: 34.95		WDTC1_MOUSE (21-272): 7.36e-30: 120: 19.22
+	Hs
		609610 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		CHIP_HUMAN (1-303): 3.8e-69: 218: 100.00
+	Hs
		609537 FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29		UN45A_HUMAN (15-161): 8.39e-42: 155: 29.30