HitPredict

Interactor 1: CLIP1 (P30622)
CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin)
Gene: CLIP1

Interactor 2: CLIP1 (P30622)
CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin)
Gene: CLIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.812

The method score is based on:

Property Details
Experiments 17828275, 17828277
Identification Methods surface plasmon resonance, pull down, nuclear magnetic resonance, isothermal titration calorimetry
Interaction Type putative self interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CAP_GLY~CAP_GLY, CAP_GLY~CLIP1_ZNF
Common GO terms GO:0000278 - mitotic cell cycle
GO:0000776 - kinetochore
GO:0001578 - microtubule bundle formation
GO:0001726 - ruffle
GO:0005634 - nucleus
and 14 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 1438
Hs

1 1438
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024