HitPredict

Interactor 1: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Interactor 2: MCM7 (P38132)
DNA replication licensing factor MCM7 (EC 3.6.4.12) (Cell division control protein 47) (Minichromosome maintenance protein 7)
Gene: MCM7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.985

The method score is based on:

Property Details
Experiments 25342810, 23499444, 26255844, 15723534, 26686640, 25172955, 18662997, 19661920, 19896182, 19913425, 18801730, 22421151, 22433841, 17895243, 32804080, 35296675, 37968396, 24692448, 12480933
Identification Methods affinity chromatography technology, biochemical, pull down, x-ray crystallography, two hybrid, anti tag coimmunoprecipitation, molecular sieving
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains MCM~MCM, MCM~MCM_lid, MCM~MCM_N, MCM~MCM_OB, MCM_N~MCM_N, MCM_N~MCM_OB, MCM_OB~MCM_OB
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003688 - DNA replication origin binding
GO:0003697 - single-stranded DNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 17 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 933
Sc

1 845
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Last updated: 15 Jul 2024