HitPredict

Interactor 1: TYY1 (P25490)
Transcriptional repressor protein YY1 (Delta transcription factor) (INO80 complex subunit S) (NF-E1) (Yin and yang 1) (YY-1)
Gene: YY1

Interactor 2: SLX4 (Q8IY92)
Structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12)
Gene: SLX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37059091
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000724 - double-strand break repair via homologous recombination GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 414 Hs			1 1834
+	Hs
		188619 TYY2_HUMAN (1-411): 4.02e-100: 304: 54.99		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		1314466 ZN629_HUMAN (303-409): 2.47e-14: 77: 40.74		SLX4_HUMAN (1-1834): 0: 1473: 100.00
+	Hs
		675402 TYY1_HUMAN (1-414): 1.67e-137: 401: 100.00		KI67_HUMAN (889-1833): 6.4e-23: 109: 11.20
+	Hs
		675555 TYY1_HUMAN (1-414): 1.67e-137: 401: 100.00		SRCAP_HUMAN (982-1802): 3.8e-21: 104: 10.50
+	Hs
		675501 TYY1_HUMAN (1-414): 1.67e-137: 401: 100.00		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56
+	Hs
		675742 TYY1_HUMAN (1-414): 1.67e-137: 401: 100.00		CABIN_HUMAN (864-1723): 7.69e-09: 63.1: 10.42
+	Hs
		1129719 ZN251_HUMAN (36-295): 5.27e-43: 161: 8.10		MDC1_HUMAN (757-1462): 4.4e-17: 90.6: 10.56