HitPredict

Interactor 1: ILEU (P30740)
Leukocyte elastase inhibitor (LEI) (Monocyte/neutrophil elastase inhibitor) (EI) (M/NEI) (Peptidase inhibitor 2) (PI-2) (Serpin B1)
Gene: SERPINB1

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 379 Hs			1 317
+	Hs
		397016 PAI2_HUMAN (1-379): 6.72e-164: 467: 45.67		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		817802 SPB8_HUMAN (1-379): 9.43e-160: 454: 51.98		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818577 SPB13_HUMAN (1-379): 3.11e-156: 446: 45.46		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818366 SPB12_HUMAN (1-379): 1.14e-148: 428: 40.99		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		271857 SPB7_HUMAN (1-379): 1.57e-145: 418: 38.56		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		738732 SPB5_HUMAN (1-379): 1.41e-144: 416: 39.31		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		344108 ANT3_HUMAN (3-379): 7.85e-143: 415: 39.28		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		344176 A1AT_HUMAN (2-379): 5.31e-143: 413: 30.63		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		397097 PAI1_HUMAN (4-379): 1.07e-134: 392: 29.74		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		668017 SPB3_HUMAN (1-379): 2.22e-153: 439: 48.23		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		331682 AACT_HUMAN (4-379): 4.5e-146: 421: 34.47		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		331681 A1AT_HUMAN (2-379): 5.31e-143: 413: 30.63		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71