HitPredict

Interactor 1: GCH1 (P30793)
GTP cyclohydrolase 1 (EC 3.5.4.16) (GTP cyclohydrolase I) (GTP-CH-I)
Gene: GCH1

Interactor 2: MAEA (Q7L5Y9)
E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP)
Gene: MAEA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 250 Hs			1 396
+	Hs
		675854 GCH1_HUMAN (1-250): 8.76e-152: 424: 100.00		RMD5A_HUMAN (21-395): 8.17e-121: 357: 20.41
+	Hs
		675859 GCH1_HUMAN (1-250): 8.76e-152: 424: 100.00		GID8_HUMAN (101-284): 3.5e-47: 162: 20.32
+	Hs
		675848 GCH1_HUMAN (1-250): 8.76e-152: 424: 100.00		RANB9_HUMAN (116-215): 3.98e-25: 109: 17.00
+	Hs
		675835 GCH1_HUMAN (1-250): 8.76e-152: 424: 100.00		RBP10_HUMAN (114-215): 1.14e-23: 104: 15.69