HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: YRB1 (P41920)
Ran-specific GTPase-activating protein 1 (Chromosome stability protein 20) (Perinuclear array-localized protein) (Ran-binding protein 1) (RANBP1)
Gene: YRB1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 1.00 0.902

The method score is based on:

Property Details
Experiments 11251069, 10825193, 28282025, 31021318
Identification Methods affinity chromatography technology, two hybrid, coimmunoprecipitation, x-ray crystallography, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CRM1_C~Ran_BP1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0031267 - small GTPase binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1084
Sc

1 201
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Last updated: 15 Jul 2024