HitPredict

Interactor 1: XPO1 (P30822)
Exportin-1 (Chromosome region maintenance protein 1) (Karyopherin-124)
Gene: CRM1

Interactor 2: NU145 (P49687)
Nucleoporin NUP145 (EC 3.4.21.-) (Nuclear pore protein NUP145) [Cleaved into: Nucleoporin NUP145N (N-NUP145); Nucleoporin NUP145C (C-NUP145)]
Gene: NUP145

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	9368759
Identification Methods	two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1084 Sc			1 1317
+	Hs
		162244 XPO1_HUMAN (3-1084): 0: 854: 46.40		GANP_HUMAN (5-391): 7.98e-18: 92: 13.36
+	Hs
		162534 XPO1_HUMAN (3-1084): 0: 854: 46.40		NUP98_HUMAN (1-435): 2.24e-14: 80.9: 13.29
+	Hs
		162281 XPO1_HUMAN (3-1084): 0: 854: 46.40		SC24D_HUMAN (4-257): 1.65e-12: 74.3: 11.97
+	Hs
		162539 XPO1_HUMAN (3-1084): 0: 854: 46.40		SC24C_HUMAN (2-178): 3.19e-11: 70.1: 12.64
+	Hs
		162517 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		162448 XPO1_HUMAN (3-1084): 0: 854: 46.40		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43
+	Xl
		1145048 Q6NS03_XENLA (3-1084): 0: 852: 46.77		Q641I5_XENLA (2-159): 5.75e-09: 62.8: 13.04
+	Sc
		676300 XPO1_YEAST (1-1084): 0: 833: 100.00		NU100_YEAST (45-542): 1.84e-14: 80.8: 14.10
+	Sc
		541850 XPO1_YEAST (1-1084): 0: 833: 100.00		NSP1_YEAST (3-459): 5.33e-11: 69.3: 13.35
+	Sc
		676195 XPO1_YEAST (1-1084): 0: 833: 100.00		NUP57_YEAST (118-368): 1.26e-10: 67.7: 15.33
+	Sc
		676301 XPO1_YEAST (1-1084): 0: 833: 100.00		NU116_YEAST (43-484): 6.18e-10: 66.2: 12.29
+	Sc
		676294 XPO1_YEAST (1-1084): 0: 833: 100.00		NUP49_YEAST (3-140): 3.57e-10: 66.1: 29.68
+	Sc
		676197 XPO1_YEAST (1-1084): 0: 833: 100.00		NUP42_YEAST (2-285): 1.65e-09: 63.8: 17.86
+	Sc
		676117 XPO1_YEAST (1-1084): 0: 833: 100.00		NU159_YEAST (2-479): 6.29e-09: 62.7: 11.43
+	Dm
		1353152 XPO1_DROME (3-1084): 0: 789: 42.48		Q9VLS7_DROME (2-487): 5.06e-13: 76.2: 11.03
+	Tt
		101847 G0RZB7_CHATD (10-1084): 0: 779: 50.19		NU145_CHATD (7-472): 2.07e-10: 67.8: 12.30
+	Hs
		980020 XPO7_HUMAN (11-1030): 8.18e-147: 469: 13.59		IF4G1_HUMAN (3-740): 5.58e-52: 203: 7.92
+	Mm
		1157646 XPO7_MOUSE (11-1030): 1.87e-146: 468: 13.68		IF4G1_MOUSE (181-742): 4.32e-13: 76.6: 9.06
+	Hs
		834682 XPO7_HUMAN (11-1030): 8.18e-147: 469: 13.59		NU153_HUMAN (16-447): 4.54e-11: 70: 10.50
+	Hs
		727340 TNPO3_HUMAN (8-1040): 5.86e-127: 412: 13.31		NU214_HUMAN (14-341): 6.71e-11: 69.6: 16.43