Protein: UTP22
U3 small nucleolar RNA-associated protein 22 (U3 snoRNA-associated protein 22) (U three protein 22)

Gene: UTP22
Organism: Saccharomyces cerevisiae S288C
Interactions: 231
UniProt ID: P53254

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

673206

RRP7
Ribosomal RNA-processing protein 7

9

1

Small-scale

0.980

High

918786

UTP22
U3 small nucleolar RNA-associated protein 22

2

0

High-throughput

0.769

High

585985

CSK21
Casein kinase II subunit alpha

8

2

High-throughput

0.753

High

678428

PWP2
Periodic tryptophan protein 2

7

3

Small-scale

0.745

High

918833

NOC4
Nucleolar complex protein 4

7

2

Small-scale

0.745

High

850999

CSK2B
Casein kinase II subunit beta

6

1

High-throughput

0.735

High

798271

ENP1
Essential nuclear protein 1

11

0

Small-scale

0.725

High

817599

UTP7
U3 small nucleolar RNA-associated protein 7

5

3

High-throughput

0.720

High

918815

DHR1
Probable ATP-dependent RNA helicase DHR1

8

0

Small-scale

0.719

High

918825

UTP21
U3 small nucleolar RNA-associated protein 21

5

3

Small-scale

0.716

High

918836

UTP4
U3 small nucleolar RNA-associated protein 4

5

3

Small-scale

0.716

High

823361

UTP18
U3 small nucleolar RNA-associated protein 18

6

0

High-throughput

0.707

High

865144

MPP10
U3 small nucleolar RNA-associated protein MPP10

6

0

Small-scale

0.707

High

918789

UTP8
U3 small nucleolar RNA-associated protein 8

6

0

Small-scale

0.706

High

812161

IFH1
Protein IFH1

6

0

Small-scale

0.702

High

918832

RRP9
Ribosomal RNA-processing protein 9

4

2

High-throughput

0.701

High

844547

UTP10
U3 small nucleolar RNA-associated protein 10

6

0

High-throughput

0.701

High

747029

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

4

2

High-throughput

0.697

High

782082

RL1D1
Ribosome biogenesis protein UTP30

4

1

High-throughput

0.697

High

918807

UTP17
NET1-associated nuclear protein 1

4

4

High-throughput

0.697

High

918835

BFR2
Protein BFR2

4

1

High-throughput

0.697

High

918859

UTP12
U3 small nucleolar RNA-associated protein 12

4

3

High-throughput

0.697

High

918796

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

4

2

Small-scale

0.696

High

918869

NOP14
Nucleolar complex protein 14

5

0

High-throughput

0.694

High

622985

CSK22
Casein kinase II subunit alpha'

4

1

High-throughput

0.694

High

807773

CSK2C
Casein kinase II subunit beta'

4

1

High-throughput

0.694

High

918865

NOP58
Nucleolar protein 58

4

2

High-throughput

0.694

High

852581

ROK1
ATP-dependent RNA helicase ROK1

5

0

High-throughput

0.692

High

763597

UTP20
U3 small nucleolar RNA-associated protein 20

5

0

High-throughput

0.691

High

918805

UTP6
U3 small nucleolar RNA-associated protein 6

5

0

High-throughput

0.691

High

918819

RRP5
rRNA biogenesis protein RRP5

4

1

Small-scale

0.687

High

918798

NAT10
RNA cytidine acetyltransferase

5

0

High-throughput

0.686

High

918822

RRP45
Exosome complex component RRP45

4

3

High-throughput

0.678

High

585320

FBRL
rRNA 2'-O-methyltransferase fibrillarin

3

1

High-throughput

0.671

High

871032

NOL10
Ribosome biogenesis protein ENP2

4

0

High-throughput

0.667

High

918829

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

4

0

High-throughput

0.667

High

383807

RS17A
Small ribosomal subunit protein eS17A

3

1

High-throughput

0.667

High

677497

KRR1
KRR1 small subunit processome component

4

0

High-throughput

0.666

High

792159

GBLP
Small ribosomal subunit protein RACK1

3

2

High-throughput

0.662

High

918830

ESF1
Pre-rRNA-processing protein ESF1

3

0

Small-scale

0.643

High

918818

UTP14
U3 small nucleolar RNA-associated protein 14

3

0

High-throughput

0.643

High

918787

RRP46
Exosome complex component RRP46

3

3

High-throughput

0.643

High

918841

RRP44
Exosome complex exonuclease DIS3

3

1

High-throughput

0.643

High

779143

DHR2
Probable ATP-dependent RNA helicase DHR2

2

1

High-throughput

0.643

High

513127

RS8A
Small ribosomal subunit protein eS8A

3

1

Small-scale

0.640

High

436074

RS13
Small ribosomal subunit protein uS15

3

0

High-throughput

0.638

High

689569

RS7A
Small ribosomal subunit protein eS7A

3

0

High-throughput

0.638

High

806546

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.638

High

918845

UTP16
U3 small nucleolar RNA-associated protein 16

3

0

High-throughput

0.638

High

632709

DBP4
ATP-dependent RNA helicase HCA4

2

3

High-throughput

0.637

High

918814

UTP5
U3 small nucleolar RNA-associated protein 5

2

3

High-throughput

0.637

High

836189

DIM1
Dimethyladenosine transferase

3

0

High-throughput

0.634

High

918839

CMS1
Protein CMS1

3

0

High-throughput

0.634

High

918870

PNO1
Pre-rRNA-processing protein PNO1

3

0

High-throughput

0.634

High

149872

RS9A
Small ribosomal subunit protein uS4A

3

2

High-throughput

0.633

High

655492

RS3A2
Small ribosomal subunit protein eS1B

2

2

High-throughput

0.628

High

918826

MRD1
Multiple RNA-binding domain-containing protein 1

2

1

Small-scale

0.628

High

814348

NOC2
Nucleolar complex protein 2

3

0

High-throughput

0.622

High

830146

NOP2
25S rRNA

3

0

High-throughput

0.622

High

918820

FCF1
rRNA-processing protein FCF1

2

1

High-throughput

0.614

High

918824

UTP13
U3 small nucleolar RNA-associated protein 13

2

4

High-throughput

0.614

High

524655

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.611

High

825541

UTP25
U3 small nucleolar RNA-associated protein 25

2

0

High-throughput

0.610

High

569830

RL30
Large ribosomal subunit protein eL30

2

0

High-throughput

0.602

High

688928

RS5
Small ribosomal subunit protein uS7

2

0

High-throughput

0.602

High

545688

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.601

High

918790

NOP19
Nucleolar protein 19

2

0

Small-scale

0.588

High

918855

SAS10
Something about silencing protein 10

2

0

High-throughput

0.588

High

754497

RT05
Small ribosomal subunit protein uS5m

2

1

High-throughput

0.588

High

863932

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

2

1

High-throughput

0.588

High

918842

BRX1
Ribosome biogenesis protein BRX1

2

4

High-throughput

0.588

High

826195

FAF1
Protein FAF1

2

0

Small-scale

0.585

High

918864

RRP36
rRNA biogenesis protein RRP36

2

0

Small-scale

0.585

High

864480

MTR4
ATP-dependent RNA helicase DOB1

2

1

Small-scale

0.584

High

918792

ESF2
Pre-rRNA-processing protein ESF2

2

1

Small-scale

0.584

High

918800

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

2

2

High-throughput

0.584

High

918858

PUS1
tRNA pseudouridine synthase 1

2

0

High-throughput

0.563

High

512123

RS4A
Small ribosomal subunit protein eS4A

2

0

High-throughput

0.559

High

513892

RS11B
Small ribosomal subunit protein uS17B

2

0

High-throughput

0.559

High

672918

RRP43
Exosome complex component RRP43

2

0

High-throughput

0.559

High

826688

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

918793

CSL4
Exosome complex component CSL4

2

0

High-throughput

0.559

High

918856

RRP6
Exosome complex exonuclease RRP6

2

0

High-throughput

0.559

High

802883

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.558

High

918795

SQS1
Protein SQS1

1

0

High-throughput

0.558

High

527260

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

819351

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

753008

XPOT
Exportin-T

1

0

Small-scale

0.537

High

783492

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

0

Small-scale

0.537

High

570284

RS17B
Small ribosomal subunit protein eS17B

1

1

High-throughput

0.536

High

812174

FKHL1
Pre-rRNA-processing protein FHL1

1

1

Small-scale

0.536

High

918808

GCN5
Histone acetyltransferase GCN5

1

2

High-throughput

0.536

High

918601

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

918837

TSR1
Ribosome biogenesis protein TSR1

1

1

High-throughput

0.515

High

449422

SPT2
Protein SPT2

1

0

High-throughput

0.513

High

644666

MAG
DNA-3-methyladenine glycosylase

1

0

High-throughput

0.513

High

646477

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.513

High

651968

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.513

High

676751

GBP2
Serine/arginine

1

0

High-throughput

0.513

High

735271

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.513

High

744803

ALK2
Serine/threonine-protein kinase Haspin homolog ALK2

1

0

High-throughput

0.513

High

820381

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.513

High

917434

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.513

High

918794

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

918811

CTK1
CTD kinase subunit alpha

1

0

High-throughput

0.513

High

918813

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.513

High

665192

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.493

High

780290

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.493

High

809375

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

828497

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.493

High

908509

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

High-throughput

0.493

High

918812

HMO1
High mobility group protein 1

1

0

High-throughput

0.493

High

918847

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.493

High

918848

RKM1
Ribosomal lysine N-methyltransferase 1

1

0

High-throughput

0.493

High

918852

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.493

High

602576

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

435245

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

512557

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

633178

MAK11
Protein MAK11

1

2

Small-scale

0.479

High

645474

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

670958

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

674738

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

682346

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

747487

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.479

High

753490

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

754309

DCA13
Protein SOF1

1

2

High-throughput

0.479

High

793504

MAK5
ATP-dependent RNA helicase MAK5

1

3

High-throughput

0.479

High

803893

CIC1
Proteasome-interacting protein CIC1

1

1

High-throughput

0.479

High

804729

RRP4
Exosome complex component RRP4

1

1

High-throughput

0.479

High

808289

RRP8
25S rRNA

1

2

High-throughput

0.479

High

863113

RRP41
Exosome complex component SKI6

1

3

High-throughput

0.479

High

918799

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

918801

H3
Histone H3

1

1

High-throughput

0.479

High

918806

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

918809

HAS1
ATP-dependent RNA helicase HAS1

1

3

High-throughput

0.479

High

918816

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.479

High

918849

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.479

High

918857

MAK21
Ribosome biogenesis protein MAK21

1

2

High-throughput

0.479

High

918860

RRP42
Exosome complex component RRP42

1

3

High-throughput

0.479

High

918862

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.479

High

918863

NOP56
Nucleolar protein 56

1

2

High-throughput

0.479

High

918866

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.479

High

382240

H4
Histone H4

1

0

High-throughput

0.458

High

410247

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

433755

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

436472

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

442025

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

455172

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

594483

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

603086

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

707733

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709888

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

735076

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

747961

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

751438

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.458

High

758390

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

778447

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

804941

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

818322

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.458

High

825064

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

826038

ULP2
Ubiquitin-like-specific protease 2

1

0

High-throughput

0.458

High

827561

RLP7
Ribosome biogenesis protein RLP7

1

0

High-throughput

0.458

High

864938

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

865401

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

871108

MTR3
Exosome complex component MTR3

1

0

High-throughput

0.458

High

874434

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

917537

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.458

High

918788

PESC
Pescadillo homolog

1

0

High-throughput

0.458

High

918791

PXR1
Protein PXR1

1

0

Small-scale

0.458

High

918804

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

918817

BUD22
Bud site selection protein 22

1

0

High-throughput

0.458

High

918821

HRQ1
ATP-dependent helicase HRQ1

1

0

Small-scale

0.458

High

918827

SGD1
Suppressor of glycerol defect protein 1

1

0

High-throughput

0.458

High

918828

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

918834

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

918840

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.458

High

918843

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

918844

SGO1
Shugoshin

1

0

High-throughput

0.458

High

918846

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.458

High

918850

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

918853

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

918867

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

918868

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.458

High

393079

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.445

High

435608

RS9B
Small ribosomal subunit protein uS4B

1

2

High-throughput

0.445

High

676198

MAS5
Mitochondrial protein import protein MAS5

1

2

High-throughput

0.445

High

742049

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

742905

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

811358

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

811478

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

918861

UTP23
rRNA-processing protein UTP23

1

1

High-throughput

0.445

High

504326

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

511241

RL20B
Large ribosomal subunit protein eL20B

1

1

High-throughput

0.437

High

394761

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

518083

SSBP1
Single-stranded nucleic acid-binding protein

1

0

High-throughput

0.426

High

570088

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.426

High

590684

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

597222

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

692595

NSR1
Nuclear localization sequence-binding protein

1

0

High-throughput

0.426

High

782393

RPF2
Ribosome biogenesis protein RPF2

1

0

High-throughput

0.426

High

804325

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

806982

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.426

High

918851

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.426

High

579793

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.407

High

737751

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

1

High-throughput

0.407

High

918823

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

2

High-throughput

0.407

High

503153

RS22A
Small ribosomal subunit protein uS8A

4

0

High-throughput

0.356

High

511829

RS24A
Small ribosomal subunit protein eS24A

2

0

High-throughput

0.328

High

456542

ARD1
N-terminal acetyltransferase A complex catalytic subunit ARD1

2

0

High-throughput

0.313

High

918803

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.279

Low

918810

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.279

Low

918831

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.279

Low

918854

RTK1
Probable serine/threonine-protein kinase RTK1

1

0

High-throughput

0.279

Low

780623

CAB3
Coenzyme A biosynthesis protein 3

1

0

High-throughput

0.269

Low

818508

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.269

Low

826369

SGN1
RNA-binding protein SGN1

1

0

High-throughput

0.269

Low

918797

TDA7
Topoisomerase I damage affected protein 7

1

0

High-throughput

0.269

Low

514744

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

558814

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

748478

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

800669

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.249

Low

802289

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

812511

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

918410

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

918802

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

918838

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

626828

HSP60
Heat shock protein 60, mitochondrial

1

0

High-throughput

0.232

Low

752545

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

863667

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

865015

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025