HitPredict

Interactor 1: CTR1 (P30825)
High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homolog) (Ecotropic retrovirus receptor homolog) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter)
Gene: SLC7A1

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 629 Hs			1 193
+	Hs
		676533 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436173 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		676536 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		676528 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545221 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		676527 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		676532 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120316 CTR1_HUMAN (1-629): 8.51e-169: 497: 100.00		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		854869 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		854874 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436219 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		854876 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		854866 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545280 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		854865 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		854873 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120359 CTR2_HUMAN (1-620): 4.55e-146: 439: 60.61		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		900749 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		894268 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		120564 YLAT2_HUMAN (8-494): 6.88e-98: 310: 18.74		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98