HitPredict

Interactor 1: RPB2 (P30876)
DNA-directed RNA polymerase II subunit RPB2 (EC 2.7.7.6) (3'-5' exoribonuclease) (EC 3.1.13.-) (DNA-directed RNA polymerase II 140 kDa polypeptide) (DNA-directed RNA polymerase II subunit B) (RNA polymerase II subunit 2) (RNA polymerase II subunit B2) (RNA-directed RNA polymerase II subunit RPB2) (EC 2.7.7.48)
Gene: POLR2B

Interactor 2: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.963

The method score is based on:

Property Details
Experiments 26186194, 26496610, 28514442, 24981860, 33961781, 35271311, 17643375
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_7~S1, RNA_pol_Rpb2_7~SHS2_Rpb7-N
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005665 - RNA polymerase II, core complex
GO:0006366 - transcription by RNA polymerase II
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1174
Hs

1 172
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Hs
+ Dm
+ Sc
+ Pf
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024